Pancuronium is a neuromuscular blocker used as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. A bis-quaternary steroid that is a competitive nicotinic antagonist.
- Mechanism
- Curator reviewed
Nondepolarizing neuromuscular blocking agents inhibit neuromuscular transmission by competing with acetylcholine for the cholinergic receptors of the motor end plate, thereby reducing the response of the end plate to acetylcholine. This type of neuromuscular block is usually antagonized by anticholinesterase agents.
- Primary indication
- Used as a muscle relaxant during anesthesia and surgical procedures.Curator reviewed · 3 structured indications
- Formula / weight
- C35H60N2O4 · 572.8619 g/mol (avg)
- First approval
- Canada, 2004 · United States, 1990
Resolves to
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Which drugs share a target with Pancuronium, and which of those have an active Phase 3 trial?
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