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Desirudin
go.drugbank.com/drugs/DB11095ApprovedWithdrawnDesirudin is a direct inhibitor of human thrombin. … Hirudin is a single polypeptide chain of 65 amino acids residues and contains three disulfide bridges. Desirudin has a chemical formula of C287H440N80O110S6 with a molecular weight of 6963.52.
Anidulafungin
go.drugbank.com/drugs/DB00362ApprovedThere is preliminary evidence that it has a similar safety profile to caspofungin. … Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in February 21, 2006; it was previously known as LY303366.
Products: ECALTA®, ICIN TOZ ICEREN FLAKON, 1 ADET VE COZUCUEfinaconazole
go.drugbank.com/drugs/DB09040ApprovedInvestigationalEfinaconazole is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the nail, known as onychomycosis. … It was approved for use in Canada and the USA in 2014 and is marketed by Valeant Pharmaceuticals North America LLC under the name Jublia.
Synonyms: (2R,3R)-2-(2,4-Difluorophenyl)-3-(4-methylene-1-piperidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanolCategories: Heterocyclic Compounds, 1-RingSulfoxone
go.drugbank.com/drugs/DB01145ApprovedSulfoxone is a water-soluble sulfone used as an antileprosy drug. It has been used with limited success in the treatment of dermatitis herpetiformis.
Nitrofural
go.drugbank.com/drugs/DB00336ApprovedVet approvedWithdrawnNitrofural or nitrofurazone is a topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial wounds, burns, ulcers, and skin infections.
Synonyms: 5-Nitro-2-furaldehyde semicarbazoneMixtures: MADECASSOL CBenzoin resin
go.drugbank.com/drugs/DB11222ApprovedWhile benzoin resin is used as a common ingredient in incense-making and perfumery, it is also used clinically as a mild antiseptic agent in over-the-counter products to clean sores, cuts, wounds, and … Benzoin resin is a balsamic resin obtained from the bark of several species of trees in the genus _Styrax_.
Mixtures: Blistex Kank-A, Skin-E-dip OntPoloxamer 188
go.drugbank.com/drugs/DB11333ApprovedComposed of two hydrophilic side-chains attached to a hydrophobic center core [A27218], its average molecular weight is 8400 Daltons. … Poloxamer 188 (P188) is a nonionic block linear copolymer that exhibits rheologic, anti-thrombotic, anti-inflammatory, and cytoprotective activities in various tissue injury models [A33121].
International brands: Lutrol FCategories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsPhenoxyethanol
go.drugbank.com/drugs/DB11304ApprovedInvestigationalPhenoxyethanol is a colorless liquid with a pleasant odor. … Phenoxyethanol is a colorless, clear, oily liquid with a faint aromatic odor at room temperature and a low water solubility and evaporation rate.
Synonyms: 1-Hydroxy-2-phenoxyethane, 2-phenoxyethanolMixtures: Linola sept 1 mg/g + 10 mg/g Wund-Gel, HydroGold 9Raltegravir
go.drugbank.com/drugs/DB06817ApprovedInvestigationalRaltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S. … Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.
Categories: Heterocyclic Compounds, 1-RingProducts: ISENTRESS® 600MG TABLETAS, ISENTRESS-G TABLET 400MGRopinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalRopinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], [A174547]. … It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: REQUIP TABLET 1 mg, REQUIP TABLET 2 mg