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Prenylamine
go.drugbank.com/drugs/DB04825ApprovedWithdrawnPrenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Synonyms: N-(3,3-Diphenylpropyl)-alpha-methylphenaethylamin, N-(3,3-Diphenylpropyl)-alpha-methylphenethylamineCategories: Vasodilators Used in Cardiac DiseasesNatural Killer Cell
go.drugbank.com/drugs/DB15721InvestigationalExpansion involves the use of feeder cell line systems or bioreactors to enhance the number of NK cells with desired cytotoxicity. … It is also possible to culture UCB CD34+ hematopoietic stem cells (HSCs) under stimulation of IL-2, IL-15, and stem cell factor (SCF) in a system to develop NK cells.
Hydroxyproline
go.drugbank.com/drugs/DB08847ApprovedHydroxyproline is a neutral heterocyclic protein amino acid. It is found in collagen and as such it is common in many gelatin products. … Therapeutically, hydroxyproline is being studied as an an experimental medicine but is approved in France as a combination topical gel product called Cicactive for small, superficial wounds.
Brigatinib
go.drugbank.com/drugs/DB12267ApprovedInvestigational[A31311] It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a pivotal player in the transformation of susceptible lung parenchyma. … It presents selectivity against the mutant forms of EGFR compared to the wild-type.
Lodoxamide
go.drugbank.com/drugs/DB06794ApprovedMast-cell stabilizers, first one approved being cromolyn sodium, are used in treatment of ocular hypersensitivity reactions such as vernal conjunctivitis. … Lodoxamide is marketed under the brand name Alomide by Alcon.
Synonyms: N,N'-(2-chloro-5-cyano-m-phenylene)dioxamateProflavine
go.drugbank.com/drugs/DB01123ApprovedInvestigationalTopical antiseptic used mainly in wound dressings.
Lobeglitazone
go.drugbank.com/drugs/DB09198InvestigationalLobeglitazone was approved by the Ministry of Food and Drug Safety (South Korea) in 2013, and is being monitored by postmarketing surveillance until 2019. … Lobeglitazone is not approved for use by either the Food and Drug Administration (USA), Health Canada, or by the European Medicines Agency for use in the management of diabetes.
Categories: Drugs Used in DiabetesIsavuconazole
go.drugbank.com/drugs/DB11633ApprovedInvestigationalResistance to isavuconazole has been associated with the mutation in the target gene CYP51 [FDA Label]. … In vitro, most of the _Candida_ species, most _Aspergillus_ species, Mucorales, _Cryptococcus_ spp., _Fusarium_ species, dermatophytes and dimorphic fungi displayed susceptibility to isavuconzaole [A32029
Propylhexedrine
go.drugbank.com/drugs/DB06714ApprovedPropylhexedrine is an alpha-adrenergic agonist often used in nasal decongestant inhalers. It is used to give temporary relief for nasal congestion from colds, allergic rhinitis, or allergies.