Propylhexedrine is an alpha-adrenergic agonist often used in nasal decongestant inhalers. It is used to give temporary relief for nasal congestion from colds, allergic rhinitis, or allergies.
- Mechanism
- Curator reviewed
Propylhexidrine causes the norepinephrine, dopamine, and serotonin (5HT) transporters to reverse their direction of flow. This inversion leads to a release of these transmitters from the vesicles to the cytoplasm and from the cytoplasm to the synapse. It also antagonizes the action of VMAT2, causing the release of more neurotransmitters.
- Primary indication
- It is used to provide temporary symptomatic relief of nasal congestion due to colds, allergies and allergic rhinitis.Curator reviewed · 1 structured indication
- Formula / weight
- C10H21N · 155.2804 g/mol (avg)
Resolves to
JCRIVQIOJSSCQD-UHFFFAOYSA-NSMILESCNC(C)CC1CCCCC1What you can answer from here — as of September 13, 2026
Which drugs share a target with Propylhexedrine, and which of those have an active Phase 3 trial?
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