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Follitropin
go.drugbank.com/drugs/DB00066ApprovedInvestigationalFurther, the ogliosaccharide side chains are very similar, but not completely identical to that of natural FSH. However, these small differences do not affect the bioactivity compared to natural FSH. … Given by subcutaneous injection, it is used in combination with human chorionic gonadotropin (hCG) to assist in ovulation and fertility.
Mixtures: MENOPUR 150 IU IM VE SC ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 10 ADET, PERGOVERIS 150 IU/75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 10 ADETProducts: GONAL-F 150 IU ENJEKTABL LİYOFİLİZE TOZ İÇEREN AMPUL, 1 ADET, PUREGON SOLUTION FOR INJECTION 100 iu/0.5 mlCisapride
go.drugbank.com/drugs/DB00604ApprovedWithdrawnIn many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias. … The FDA issued a warning letter regarding this risk to health care professionals and patients.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesProducts: DISPEPRID 10 MG TABLET, 50 ADET, DISPEPRID 10 MG TABLET, 30 ADETTrimethobenzamide
go.drugbank.com/drugs/DB00662ApprovedInvestigationalIn dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate. … Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ).
Mixtures: EMEDUR 100 MG/20 MG SUPOZİTUAR, 5 ADET, EMEDUR 200 MG SUPOZITUAR, 100 ADETProducts: VOMET 100 MG SUPPOZITUVAR , 5 ADET, VOMITIN 100 MG 6 AMPULMycophenolate mofetil
go.drugbank.com/drugs/DB00688ApprovedInvestigational[A180799,A180805] Previously, mycophenolic acid (MPA) was administered to individuals with autoimmune diseases beginning in the 1970s, but was discontinued due to gastrointestinal effects and concerns … It demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects when compared to MPA.[A180826]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoateIron sucrose
go.drugbank.com/drugs/DB09146ApprovedInvestigationalDue to less side effects than iron dextran, iron sucrose is more preferred in chronic kidney disease patients. … saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do
Mixtures: Myferon 150 ForteProducts: VELTIFER 100 MG/5 ML ORAL ÇÖZELTİ, 10 ADET, FERINT 100 MG/5 ML IV AMPUL ,AMPUL, 5 ADETNitrofurantoin
go.drugbank.com/drugs/DB00698ApprovedInvestigationalVet approved[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. … Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.
Synonyms: 5-Nitrofurantoin, 1-((5-nitrofurfurylidene)amino)hydantoinProducts: PIYELOSEPTYL 100 MG TABLET, 30 ADET, PIYELOSEPTYL 25 MG/5 ML ORAL SUSPANSIYON, 100 MLPiperazine
go.drugbank.com/drugs/DB00592ApprovedVet approvedWithdrawnOutside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. … Piperazine compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: ASEPAR 100 MG 100 ML SURUP, HELMICIDE 800 MG 150 ML SURUPHepatitis B immune globulin
go.drugbank.com/drugs/DB05276ApprovedInvestigationalAccording to the Centers for Disease Control and Prevention (CDC), the hepatitis B vaccine was the first anti-cancer vaccine. … Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B.
Products: IVHEBEX 5000 IU/100 ML IV INF. ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET, HEPATECT CP 500 IU 10 ML FLAKONBromhexine
go.drugbank.com/drugs/DB09019ApprovedInvestigational[A233240] Recently, bromhexine and its metabolite [ambroxol] have garnered interest for the potential prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs.
Mixtures: TO-FLEM (GUAYACOLATO+BROMHEXINA), ROBITUSSIN MEProducts: BROMEK 5 ML 4 MG SURUP, 100 ML, BROMEKSIN 80 MG 100 ML SURUPTrastuzumab emtansine
go.drugbank.com/drugs/DB05773ApprovedInvestigationalT-DM1 combines two strategies-- anti-HER2 activity and targeted intracellular delivery of the potent anti-microtubule agent, DM1 (a maytansine derivative)--to produce cell cycle arrest and apoptosis. … Trastuzumab emtansine, formerly called Trastuzumab-DM1 (T-DM1) is a first-in-class HER2 antibody drug conjugate (ADC) comprised of Genentech's trastuzumab antibody linked to ImmunoGen's cell-killing agent
Synonyms: T-DM1Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates