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Carboplatin
go.drugbank.com/drugs/DB00958ApprovedInvestigational[A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.[L32248] … Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.[L32253] Early clinical studies of carboplatin were performed in 1982.
Categories: Compounds used in a research, industrial, or household settingProducts: PLATINWAS 150 MG 10MG/ML ENJ. FLAKON, 1 ADET, PLATINWAS 450 MG 10MG/ML ENJ. FLAKON, 1 ADETTranexamic acid
go.drugbank.com/drugs/DB00302ApprovedInvestigational[L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986.[L31858] … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding.
Products: ACIDO TRANEXAMICO EG, TRANSAMINE 50 MG/ML IV ENJ COZELTI, 5 MLArsenic trioxide
go.drugbank.com/drugs/DB01169ApprovedInvestigationalArsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. … In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous adverse effects.
Products: ARSENICO TRIOSSIDO EGCyclobenzaprine
go.drugbank.com/drugs/DB00924ApprovedInvestigationalCyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been available for human use since 1977. … [A184982] It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from [Amitriptyline] by only a single double bond.
Synonyms: N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-Δ5,γ-propylamineProducts: Cyclobenzaprine HCL ERSevelamer
go.drugbank.com/drugs/DB00658ApprovedInvestigationalSevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Categories: Compounds used in a research, industrial, or household settingProducts: SEVELAMER EG, SEVELAMER EG STADATamsulosin
go.drugbank.com/drugs/DB00706ApprovedInvestigational[A178351] Tamsulosin was first approved by the FDA on April 15, 1997.[L6238] … [Label] Other alpha-1 adrenoceptor antagonists developed in the 1980s were less selective and more likely to act on the smooth muscle of blood vessels, resulting in hypotension.
Mixtures: DUTASTERIDE E TAMSULOSINA DOC, DUTASTERIDE E TAMSULOSINA DOCCategories: Drugs Used in Benign Prostatic HypertrophyPramocaine
go.drugbank.com/drugs/DB09345ApprovedPramocaine is available by itself and in combination with other medications in various topical preparations.
Mixtures: Gold Bond Anti Itch, Gold Bond Anti ItchProducts: First On Topical Analgesic, Bikini Zone Medicated After-shave Roll-ON ReliefCefonicid
go.drugbank.com/drugs/DB01328ApprovedIt is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
Synonyms: (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-8-oxo-3-({[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acidProducts: CEFONICID EGEszopiclone
go.drugbank.com/drugs/DB00402ApprovedInvestigationalEszopiclone was initially approved by the FDA in 2004.[L6769]
International brands: Wen FeiProducts: DORMEBEN® EZ 2 MG TABLETAS RECUBIERTAS., DORMEBEN® EZ 3 MG TABLETAS RECUBIERTASDiltiazem
go.drugbank.com/drugs/DB00343ApprovedInvestigational[L6289] Typically available in extended-release oral and intravenous formulations, diltiazem is marketed under various brand names with Cardizem and Tiazac being the most common ones. … [L10556] Compared to dihydropyridine drugs, such as [nifedipine], that preferentially act on vascular smooth muscle and [verapamil] that directly acts on the heart muscle, diltiazem displays an intermediate
Products: Tiadylt ER, DILTIAZEM EG