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Ivermectin
go.drugbank.com/drugs/DB00602ApprovedInvestigationalVet approvedin favour of thoroughly-vetted therapies (e.g. … While studies are still ongoing, much of the evidence for ivermectin in COVID-19 relies on pre-print _in vitro_ data, and the clinical utility of this data remains unclear.
Categories: Compounds used in a research, industrial, or household settingProducts: IVERMECTINA 0.6% SOLUCIÓN EN GOTAS, SOOLANTRA CREAM 10MG/GEbastine
go.drugbank.com/drugs/DB11742ApprovedInvestigationalWithdrawnEbastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.
Products: EBASTINA EG, EBASTEL 10MGAcalabrutinib
go.drugbank.com/drugs/DB11703ApprovedInvestigationalunmet medical need based on a surrogate endpoint. … [L42795,L42800] Unlike Calquence capsules, the co-administration of Calquence tablets and PPIs does not have an effect in the pharmacokinetics of acalabrutinib.
Products: CALQUENCE® 100MG, CALQUENCE HARD CAPSULES 100MGGolimumab
go.drugbank.com/drugs/DB06674ApprovedInvestigationalThus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with moderate to severe active rheumatoid arthritis (RA), (ii) alone or as an adjunct to methotrexate … treatment in patients with active psoriatic arthritis (PsA), (iii) as a single agent in patients with active ankylosing spondylitis (AS), and (iv) as a single agent in patients with moderate to severe
Products: SIMPONI 100MG ILO IN FER, SIMPONI 100MG FERVerapamil
go.drugbank.com/drugs/DB00661ApprovedInvestigationalinto therapy in the early 1960s. … Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced
Mixtures: Trandolapril and Verapamil Hydrochloride ER, Trandolapril and Verapamil Hydrochloride ERInternational brands: Verogalid ER, VerminRizatriptan
go.drugbank.com/drugs/DB00953ApprovedInvestigational[L46018] Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. … [L46018] Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film formulations.
Synonyms: N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine, N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamineProducts: RIZATRIPTAN EG, MAXALT 10MGAmoxapine
go.drugbank.com/drugs/DB00543ApprovedThey contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, amoxapine does not affect mood or arousal, but may cause sedation. … The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission.
Products: Asendin Tab 100mg, Asendin - Tab 100mgClozapine
go.drugbank.com/drugs/DB00363ApprovedInvestigationalDespite its effectiveness in treating both positive and negative symptoms of schizophrenia, clozapine was briefly removed from the market in various jurisdictions in 1970 due to severe agranulocytosis. … Clozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent.
Products: Gen-clozapine, LEPONEX 100MGHaloperidol
go.drugbank.com/drugs/DB00502ApprovedInvestigational[A180625] The efficacy of haloperidol was first established in controlled trials in the 1960s.[A180610] … However, these findings contradict the findings from studies in vitro with human liver microsomes and from drug interaction studies in vivo.
Products: -im 100mg/ml, Liq Im 100mg/mlTestosterone propionate
go.drugbank.com/drugs/DB01420ApprovedInvestigationalVet approvedWithdrawnCurrently, this drug has been discontinued in humans, but the vet application is still available as an OTC.[L1160] … [T83] Testosterone propionate was developed initially by Watson labs, and FDA approved on February 5, 1974.
Products: Malogen In Oil Liq 100mg/ml, Testosterone Propionate Inj 100mg/ml