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Tizanidine
go.drugbank.com/drugs/DB00697ApprovedInvestigationalTizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury [T574]. … It may also be caused by musculoskeletal injury [A177583]. Regardless of the cause, muscle spasticity can be an extremely painful and debilitating condition.
Mixtures: ALGI - B® TABLETAS, ALGI - B® TABLETASCategories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesZopiclone
go.drugbank.com/drugs/DB01198ApprovedInvestigationalZopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylateHydrochlorothiazide
go.drugbank.com/drugs/DB00999ApprovedInvestigationalVet approved[A185138] Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers.
Mixtures: Mar-candesartan / Hctz, Mar-candesartan / HctzCategories: Heterocyclic Compounds, 2-RingEnsovibep
go.drugbank.com/drugs/DB19078InvestigationalEnsovibep is under investigation in clinical trial NCT04501978 (ACTIV-3: Therapeutics for Inpatients With COVID-19).
Synonyms: Designed ankyrin repeat protein (synthetic bivalent human albumin-binding) fusion protein with designed ankyrin repeat protein (synthetic trivalent severe acute respiratory syndrome coronavirus 2 spikeFebuxostat
go.drugbank.com/drugs/DB04854ApprovedInvestigational[A230548] In February 2019, a black box warning for febuxostat was added, based on the findings of a post-market clinical study (the CARES trial) where there was an increased risk of cardiovascular … Febuxostat works by inhibiting the activity of an enzyme that is responsible for the synthesis of uric acid, thereby reducing serum uric acid levels.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: 2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acidOxidronic acid
go.drugbank.com/drugs/DB14159ApprovedSynonyms: HMD-PProducts: OSTEOCIS KIT PARA PREPARACIÓNDE OXIDRONATO DE TECNECIO ( 99M TC), TECHNESCAN HDP FOR INJECTION 3 mg/vialEdetate calcium disodium anhydrous
go.drugbank.com/drugs/DB14598ApprovedInvestigationalEdetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: Calcium Edetate de SodiumClidinium
go.drugbank.com/drugs/DB00771ApprovedClidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract.
Synonyms: Bromuro de clidinio, Bromure de ClidiniumHydrotalcite
go.drugbank.com/drugs/DB13322ApprovedInvestigationalWithdrawnProducts: ALKA - SELTZER RA REGULADOR DE ACIDEZ - SUSPENSION, ALKA SELTZER RA REGULADOR DE ACIDEZ TABLETAS MASTICABLESTopiramate
go.drugbank.com/drugs/DB00273ApprovedInvestigational[L10550] Characteristics that distinguish topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and 40% of its mass accounted for by oxygen. … Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines.[A175249] It was initially approved by the FDA in 1996.
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InducersSynonyms: 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate, 2,3:4,5-di-O-isopropylidene-β-D-fructopyranose sulfamate