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Displaying results 321 - 330 of 8170 in total
  1. Drug

    Indapamide

    go.drugbank.com/drugs/DB00808
    ApprovedInvestigational

    [A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Nu-indapamide, COMPRIMIDOS RECUBIERTOS DE LIBERACION PROLONGADA
  2. Drug

    Tretinoin

    go.drugbank.com/drugs/DB00755
    ApprovedInvestigationalNutraceutical

    [A257474] It is an oxidation product in the physiological pathway of vitamin A metabolism.

    Mixtures: AE BAN CREMA, Dr. Throwers HydrotetCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 Substrates
  3. Drug

    Sulbactam

    go.drugbank.com/drugs/DB09324
    ApprovedInvestigational

    Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resis...

    Mixtures: SULAMP® DUO TABLETA RECUBIERTAProducts: PENTICLOX-DUO
  4. Drug

    Spironolactone

    go.drugbank.com/drugs/DB00421
    ApprovedInvestigational

    Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed pur...

    Mixtures: SPIRO D TABLINEN 100MGCategories: P-glycoprotein inducers, Cytochrome P-450 CYP2C8 Inhibitors
  5. Drug

    Cefixime

    go.drugbank.com/drugs/DB00671
    ApprovedInvestigational

    [A232920, A232925, A232930] Cefixime is a broad-spectrum antibiotic and an orally-active third-generation semisynthetic cephalosporin. … [A262894,A263011 ,L49293] Cephalosporins are beta-lactam antibiotics and can be used to treat gram-positive and gram-negative bacterial infections which include conditions such as skin infections, resistant

    Products: SUPRAX DT 400MG DAĞILABİLİR TABLET, 5 ADET, SUPRAX DT 400MG DAĞILABİLİR TABLET, 10 ADET
  6. Drug

    Mesalazine

    go.drugbank.com/drugs/DB00244
    ApprovedInvestigational

    An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease [A174022].

    Synonyms: p-AminosalicylsaeureProducts: MELAZ 500 MG TABLETA DE LIBERACION RETARDADA, PENTASA®1 G GRANULOS DE LIBERACION PROLONGADA
  7. Drug

    Famotidine

    go.drugbank.com/drugs/DB00927
    ApprovedInvestigational

    Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal refl...

    Mixtures: DUO Fusion, DUO FusionCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  8. Drug

    Risperidone

    go.drugbank.com/drugs/DB00734
    ApprovedInvestigational

    [L12885] Schizophrenia and various mood disorders are thought to be caused by an excess of dopaminergic D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways … Risperidone is thought to reduce this overactivity through inhibition of dopaminergic D2 receptors and serotonergic 5-HT2A receptors in the brain.

    Categories: Dopamine D2 Receptor Antagonists, P-glycoprotein substratesProducts: Ran-risperidone, RISPERIDONE DI RENZO
  9. Drug

    Phenytoin

    go.drugbank.com/drugs/DB00252
    ApprovedInvestigationalVet approved

    [A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications … [A188826,A188832] Clinicians are advised to initiate therapeutic drug monitoring in patients who require phenytoin since even small deviations from the recommended therapeutic range can lead to suboptimal

    Categories: Cytochrome P-450 CYP1A2 Inducers, P-glycoprotein substratesSynonyms: PR-122 (redox-phenytoin)
  10. Drug

    Colistimethate

    go.drugbank.com/drugs/DB01111
    ApprovedInvestigationalVet approved

    Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms.

    Products: COLISTIMETATO DE SODIO, COLISTIMETATO DE SODIO 2 MUI