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Displaying results 321 - 330 of 1342 in total
  1. Drug

    Risankizumab

    go.drugbank.com/drugs/DB14762
    ApprovedInvestigational

    Risankizumab is a fully humanized IgG1 monoclonal antibody (mAb) directed against interleukin 23 (IL-23).

  2. Drug

    Tezepelumab

    go.drugbank.com/drugs/DB15090
    ApprovedInvestigational

    Blocking the interaction of TSLP with the receptors TSLPR and IL-7Rα improves asthma-associated biomarkers including eosinophil counts and IgE, FeNO, IL-5, and IL-13 levels. … [A243764, A243769] Thymic stromal lymphopoietin (TSLP), an innate pleiotropic IL-2-family cytokine, has emerged as a key upstream regulator of chronic inflammation across asthma endotypes.

  3. Drug

    Lanolin

    go.drugbank.com/drugs/DB11112
    Approved

    Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the coun...

    Synonyms: Wool oil, Lanolin oilMixtures: CVS A and D All-Purpose Skin Protectant, Therapeutic Bath Oil
  4. Drug

    Diethylamino hydroxybenzoyl hexyl benzoate

    go.drugbank.com/drugs/DB11269
    Approved

    in the oil phase of emulsions [F107]. … Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic photodamage, diethylamino hydroxybenzoyl hexyl benzoate is an oil-soluble UV filter that may be incorporated

    Mixtures: Kiehls Activated Sun Protector Sunscreen SPF 50 For Face and Body For All Skin Types, Kiehls Activated Sun Protector Sunscreen SPF 30 For Face and Body For All Skin Types
  5. Drug

    Icotrokinra

    go.drugbank.com/drugs/DB21724
    ApprovedInvestigational

    Icotrokinra is a first-in-class, targeted oral peptide and interleukin-23 (IL-23) receptor antagonist.

  6. Indication

    B-cell Precursor Acute Lymphoblastic Leukemia (ALL)

    go.drugbank.com/conditions/DBCOND0074417
    Drugs: Blinatumomab
    Synonyms: C-ALL, Pro-B ALL
  7. Drug

    Ataluren

    go.drugbank.com/drugs/DB05016
    ApprovedWithdrawn

    Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk.

  8. Drug

    Tocopherol

    go.drugbank.com/drugs/DB11251
    ApprovedInvestigational

    Tocopherols can be found in the diet as part of vegetable oil such as corn, soybean, sesame, and cottonseed. … [A32436] It is currently under the list of substances generally recognized as safe (GRAS) in the FDA for the use of human consumption.[L2114]

    Mixtures: Aloe Vera Sprayer, Oil
  9. Drug

    alpha-Tocopherol acetate

    go.drugbank.com/drugs/DB14003
    Approved

    RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all

    Mixtures: Insur-all Vitamin Supplement, VIL-Rx
  10. Drug

    Iron

    go.drugbank.com/drugs/DB01592
    ApprovedInvestigational

    A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems.

    Mixtures: Tl-hem 150, Tl-hem 150