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Displaying results 3291 - 3300 of 10000 in total
  1. Drug

    3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid [4-(Thiazol-2-Ylsulfamoyl)-Phenyl]-Amide

    go.drugbank.com/drugs/DB03311
    Experimental

    Synonyms: 3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid [4-(Thiazol-2-Ylsulfamoyl)-Phenyl]-Amide
  2. Drug

    Cystine

    go.drugbank.com/drugs/DB00138
    ApprovedInvestigationalNutraceuticalWithdrawn

    A covalently linked dimeric nonessential amino acid formed by the oxidation of cysteine. Two molecules of cysteine are joined together by a disulfide bridge to form cystine.

    Synonyms: (R,R)-3,3'-dithiobis(2-aminopropanoic acid), L-Cystine
  3. Drug

    Telaprevir

    go.drugbank.com/drugs/DB05521
    ApprovedWithdrawn

    Telaprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). … Telaprevir is an inhibitor of NS3/4A, a serine protease enzyme, encoded by HCV genotype 1 [FDA Label].

    Synonyms: (1S,3aR,6aS)-(2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-((1S)-1-((cyclopropylamino)oxoacetyl)butyl)octahydrocyclopenta(c)pyrrole-1-carboxamideCategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  4. Drug

    Gingerol

    go.drugbank.com/drugs/DB19255
    Investigational

    Gingerol is under investigation in clinical trial NCT05882864 (Efficacy of Ginger Muco-bioadhesive Gel in Management of Oral Lichen Planus With Immunohistochemical Analysis).

    Synonyms: (5s)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone, (s)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone
  5. Drug

    Dactinomycin

    go.drugbank.com/drugs/DB00970
    ApprovedInvestigational

    A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. … As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)

    Synonyms: N,N'-((2-AMINO-4,6-DIMETHYL-3-OXO-3H-PHENOXAZINE-1,9-DIYL)-BIS(CARBONYLIMINO(2-HYDROXYPROPYLIDENE)CARBONYLIMINOISOBUTYLIDENECARBONYL-1,2-PYRROLIDINEDIYLCARBONYL(METHYLIMINO)METHYLENECARBONYL))BIS(N-METHYL-L-VALINE, Actinomycin DCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitors
  6. Drug

    Minocycline

    go.drugbank.com/drugs/DB01017
    ApprovedInvestigational

    [A190723] Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. … [A190681] It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria.

    Synonyms: 7-Dimethylamino-6-demethyl-6-deoxytetracycline, (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamideProducts: PERIOCLINE PERIODONTAL OINTMENT 2% W/W, XELTETRA-M
  7. Drug

    5-[[trans-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid

    go.drugbank.com/drugs/DB18067
    Investigational

    Synonyms: 5-((trans-4-(4-(trifluoromethoxy)phenyl)cyclohexyl)oxy)-1h-1,2,3-triazole-4-carboxylic acid, 5-[[trans-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid
  8. Drug

    Quinine

    go.drugbank.com/drugs/DB00468
    ApprovedInvestigational

    Quinine (GLS-1200) was also investigated in clinical trials for its efficacy in preventing SARS-CoV-2 infection (NCT04408183, terminated) and is planned to be evaluated for preventing sinusitis after endoscopic … It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.

    Mixtures: IRUDERM 1Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein inhibitors
  9. Drug

    Evenamide

    go.drugbank.com/drugs/DB18775
    Investigational

    Synonyms: 2-((2-(3-butoxyphenyl)ethyl)amino)-n,n-dimethylacetamide, Acetamide, 2-((2-(3-butoxyphenyl)ethyl)amino)-n,n-dimethyl-
  10. Drug

    Lumefantrine

    go.drugbank.com/drugs/DB06708
    ApprovedInvestigational

    </i> and may be used to treat infections caused by <i>P. falciparum</i> and unidentified <i>Plasmodium</i> species, including infections acquired in chloroquine-resistant areas. … This combination therapy exerts its effects against the erythrocytic stages of <i>Plasmodium spp.

    Mixtures: ARTELERIA (ARTEMETERO 20 MG Y LUMEFANTRINA 120 MG), COARTEM ® 20/120 MG COMPRIMIDOSCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Inhibitors