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Trifarotene
go.drugbank.com/drugs/DB12808ApprovedInvestigationalTrifarotene is a topical retinoid cream used in the treatment of acne vulgaris that was first approved for use in the United States in October 2019. Retinoids are a class of medications structurally and functionally analogous to vitamin ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesCepeginterferon alfa-2B
go.drugbank.com/drugs/DB12814InvestigationalCepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic Hepatitis C).
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsTerpinen-4-ol
go.drugbank.com/drugs/DB12816InvestigationalTerpinen-4-ol is under investigation in clinical trial NCT01647217 (Demodex Blepharitis Treatment Study).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesTandospirone
go.drugbank.com/drugs/DB12833InvestigationalTandospirone has been used in trials studying the treatment of Schizophrenia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNepicastat
go.drugbank.com/drugs/DB12979InvestigationalNepicastat has been investigated for the treatment of Cocaine Dependence and Posttraumatic Stress Disorder.
Categories: P-glycoprotein substratesMephedrone
go.drugbank.com/drugs/DB13108InvestigationalMephedrone has been investigated in Alcohol-Related Disorders and Amphetamine-Related Disorders.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesLusutrombopag
go.drugbank.com/drugs/DB13125ApprovedInvestigationalLusutrombopag is an orally bioavailable thrombopoietin receptor (TPOR) agonist developed by Shionogi & Company (Osaka, Japan).
Categories: P-glycoprotein substrates, Thrombopoietin Receptor AgonistVon Willebrand factor human
go.drugbank.com/drugs/DB13133ApprovedInvestigationalThe human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the sit...
Mixtures: HAEMATE P, HAEMATE PEthyl chloride
go.drugbank.com/drugs/DB13259ApprovedWithdrawnEthyl chloride, or chloroethane, has a chemical formula C2H5Cl. It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. It was also used in other commerical applications as a chemical reagent. I...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesDiphenadione
go.drugbank.com/drugs/DB13347ExperimentalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates