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Displaying results 3301 - 3310 of 10000 in total
  1. Drug

    YKP-1358

    go.drugbank.com/drugs/DB06109
    Experimental

    YKP1358 is a novel serotonin (5-HT2A) and dopamine (D2) antagonist that has demonstrated potent activity in animals that relates to both positive and negative symptoms of schizophrenia. … In addition, the YKP1358 pharmacological profile suggests a very low potential for extrapyramidal side effects.

    Categories: Dopamine D2 Receptor Antagonists
  2. Pathway

    De Novo Triacylglycerol Biosynthesis TG(15:0/18:4(6Z,9Z,12Z,15Z)/20:5(5Z,8Z,11Z,14Z,17Z))

    smpdb.ca/view/SMP0017507
    Metabolic

    A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
  3. Drug

    Honey

    go.drugbank.com/drugs/DB14242
    ApprovedInvestigational

    Honey is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: Medi DP Energy Bar, Gongjinhyang Mi Luxury BaseSynonyms: Feng Mi
  4. Drug

    Cemiplimab

    go.drugbank.com/drugs/DB14707
    ApprovedInvestigational

    Cemiplimab is a fully human monoclonal antibody that works against programmed death receptor-1 (PD-1), which is a negative regulator of T cell function. … [L39804] Cemiplimab was first approved by the FDA on September 28, 2018, as the first FDA-approved treatment for advanced cutaneous squamous cell carcinoma (CSCC).

  5. Drug

    Deupirfenidone

    go.drugbank.com/drugs/DB19056
    Investigational

    Deupirfenidone is under investigation in clinical trial NCT05321420 (LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)).

    Synonyms: 2(1h)-pyridinone, 5-(methyl-d3)-1-phenyl-
  6. Drug

    Acetarsol

    go.drugbank.com/drugs/DB13268
    ApprovedWithdrawn

    Acetarsol, with the molecular formula N-acetyl-4-hydroxy-m-arsanilic acid, is a pentavalent arsenical compound with antiprotozoal and antihelmintic properties. … [L2622] It was first discovered in 1921 by Ernest Fourneau at the Pasteur Institute. It was developed by Neolab Inc, and approved by Health Canada as an antifungal on December 31, 1964.

  7. Drug

    Zinc sulfate, unspecified form

    go.drugbank.com/drugs/DB14548
    Approved

    Zinc sulfate is a common zinc supplement in parenteral nutrition.[A216916,L12888]

    Mixtures: Eye Drops AC, Premier Value Eye Ac
  8. Drug

    PBI-1402

    go.drugbank.com/drugs/DB05480
    Experimental

    The compound activates neutrophils, enhancing their survival and activation with comparable efficacy to GM-CSF, G-CSF and EPO, which are currently used to treat anemia. … Since it stimulates immune activity, it has been considered as a candidate for cancer treatment as well as anemia.

  9. Drug

    MGD-024

    go.drugbank.com/drugs/DB17265
    Investigational

    MGD-024 is an anti-CD123/anti-CD3 bispecific DART molecule.

  10. Drug

    gamma-Aminobutyric acid

    go.drugbank.com/drugs/DB02530
    ApprovedInvestigational

    The most common inhibitory neurotransmitter in the central nervous system.

    Mixtures: Theracodophen-750, Theracodophen-650