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Armodafinil
go.drugbank.com/drugs/DB06413ApprovedInvestigational(a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. Food and Drug Administration (FDA) in June 2007. … Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil.
Products: ARVIGIL FT COMPRIMIDOS 200MGEnlicitide
go.drugbank.com/drugs/DB22580ApprovedInvestigationalIt is formulated as enlicitide decanoate alongside the permeation enhancer sodium caprate, which facilitates absorption of the peptide across the gastrointestinal tract, though oral bioavailability remains … Across two 52-week placebo-controlled trials, enlicitide 20 mg once daily reduced LDL-C at Week 24 by 56% relative to placebo in patients with hypercholesterolemia at established or increased ASCVD risk
Oxytetracycline
go.drugbank.com/drugs/DB00595ApprovedInvestigationalVet approvedA tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
AV608
go.drugbank.com/drugs/DB05072InvestigationalIt is developed for the treatment of Social anxiety disorder (SAD), irritable bowel syndrome (IBS) and overactive bladder (OAB).
Avacincaptad pegol
go.drugbank.com/drugs/DB15165ApprovedInvestigationalIt was developed to treat an advanced form of age-related macular degeneration (AMD) called geographic atrophy (GA). … [A260801] Although anti-VEGF therapy is available for the neovascular form of AMD, no treatment was approved for GA.
Rubidium
go.drugbank.com/drugs/DB11346ApprovedWithdrawnMixtures: QBx (formerly known as PHI-5, K041059)Aminophenazone
go.drugbank.com/drugs/DB01424ApprovedWithdrawnIn biomedical applications, radiolabelled (13C-labeled) aminophenazone has been used in breath tests to measure the cytochrome P-450 metabolic activity in liver function tests.
Hexoprenaline
go.drugbank.com/drugs/DB08957ApprovedWithdrawnIt is used as a bronchodilator, antiasthmatic, and tocolytic agent.
Alvimopan
go.drugbank.com/drugs/DB06274ApprovedInvestigationalIt is used to avoid postoperative ileus following small or large bowel resection and accelerates the gastrointestinal recovery period.
Rozanolixizumab
go.drugbank.com/drugs/DB14919ApprovedInvestigational[L47122] It was granted orphan drug designation by the FDA in 2019, by the European Medicines Agency (EMA) in April 2020, and by the Japanese Pharmaceuticals and Medical Devices Agency (PMDA) in November … Rozanolixizumab-noli is available under the brand name RYSTIGGO and was developed by UCB.