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AdPEDF
go.drugbank.com/drugs/DB05138ExperimentalAdPEDF is under development for the treatment of wet age-related macular degeneration (AMD). … It has been shown to rapidly elevate the intraocular AdPEDF protein levels in the eye, inhibit abnormal blood vessel growth, and cause abnormal blood vessels to regress while protecting the eye’s photoreceptors
Mepivacaine
go.drugbank.com/drugs/DB00961ApprovedInvestigationalVet approvedIt is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route.
Mixtures: MEPISEAL-EProducts: MEPIVASTESIN INJECTION 30 mg/ml, Mepivacain Accord 10 mg/ml InjektionslösungDiosmetin
go.drugbank.com/drugs/DB11259ApprovedIt also acts as a weak TrkB receptor agonist [A27230].
Cinnamaldehyde
go.drugbank.com/drugs/DB14184ApprovedIt occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum such as camphor and cassia. Sensitivity to cinnamaldehyde may be identified with a clinical patch test.
Synonyms: (E)-3-Phenylpropenal, (E)-3-Phenyl-propenalAutologous peripheral blood-derived CD34+ cells
go.drugbank.com/drugs/DB16367ApprovedInvestigational[L27741] It is also a cell therapy being investigated by Caladrius Biosciences in the clinical trial NCT04522817 (CLBS119 for Repair of COVID-19 Induced Pulmonary Damage).
NXN-188
go.drugbank.com/drugs/DB06096InvestigationalNXN-188 is a first-in-class, dual-action small molecule incorporating both neuronal nitric oxide synthase (nNOS) inhibition and 5-HT agonism that is being developed for the treatment of acute migraine.
Daratumumab
go.drugbank.com/drugs/DB09331ApprovedInvestigational[A7935] It was first described in the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of its kind. … [L13290] It is approved for the treatment of multiple myeloma as monotherapy or combination therapy and light chain (AL) amyloidosis in combination with other drugs.
Products: DARZALEX 20 MG/ML, DARZALEX® SC 120 MG/ML SOLUCIÓN INYECTABLEOsanetant
go.drugbank.com/drugs/DB04872InvestigationalIn a review of its R&D portfolio, the company announced in August 2005 that it would cease any further development of osanetant.
Interferon alfa-2b
go.drugbank.com/drugs/DB00105ApprovedInvestigationalIt is used extensively as an antiviral or antineoplastic agent.
Products: BETAFERON 0.3 MG LIYOFILIZE TOZ ICEREN FLAKON + KULLANIMA HAZIR ENJEKTORDE COZUCU, 12 ADET, BETAFERON 0.3 MG LIYOFILIZE TOZ ICEREN FLAKON + KULLANIMA HAZIR ENJEKTORDE COZUCU, 45 ADETDalfopristin
go.drugbank.com/drugs/DB01764ApprovedIt is not effective against Enterococcus faecalis infections.