Diosmetin

DB11259ApprovedSmall molecule

Diosmetin is an O-methylated flavone and the aglycone part of the flavonoid glycosides diosmin that occurs naturally in citrus fruits . Pharmacologically, diosmetin is reported to exhibit anticancer, antimicrobial, antioxidant,... It also acts as a weak TrkB receptor agonist.

Mechanism: Pharmacologically active on Acetylcholinesterase, Maltase-glucoamylase, and Transient receptor potential cation channel subfamily V member 1
Curator reviewed
Formula / weight: C₁₆H₁₂O₆ · 300.2629 g/mol (avg)
Also known as: Luteolin 4'-methyl ether · Salinigricoflavonol

Resolves to

Compound

UNIITWZ37241OTCAS520-34-3ChEMBLCHEMBL90568ChEBI4630PubChem5281612KEGGC10038

Clinical / RWD

RxNorm1314347

Structure

InChIKeyMBNGWHIJMBWFHU-UHFFFAOYSA-NSMILESCOC1=C(O)C=C(C=C1)C1=CC(=O)C2=C(O1)C=C(O)C=C2O

Targets

P22303ACHEO43451MGAMQ8NER1TRPV1P47989XDHP40763STAT3Q16678CYP1B1

What you can answer from here — as of September 15, 2026

6Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

6Marketed productsAcross 1 country and 1 labeller

18+ReferencesStructured and connected to the statements they support

Which drugs share a target with Diosmetin, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account