Diosmetin

DB11259ApprovedSmall molecule

Diosmetin is an O-methylated flavone and the aglycone part of the flavonoid glycosides diosmin that occurs naturally in citrus fruits . Pharmacologically, diosmetin is reported to exhibit anticancer, antimicrobial, antioxidant,... It also acts as a weak TrkB receptor agonist.

Chemical structure of Diosmetin
Formula / weight
C16H12O6 · 300.2629 g/mol (avg)
Also known as
Luteolin 4'-methyl ether · Salinigricoflavonol

Resolves to

Compound
UNIITWZ37241OTCAS520-34-3ChEMBLCHEMBL90568ChEBI4630PubChem5281612KEGGC10038
Clinical / RWD
RxNorm1314347
Structure
InChIKeyMBNGWHIJMBWFHU-UHFFFAOYSA-NSMILESCOC1=C(O)C=C(C=C1)C1=CC(=O)C2=C(O1)C=C(O)C=C2O
Targets
P40763STAT3Q16678CYP1B1

What you can answer from here — as of April 02, 2025

2Protein targetsEach mapped to UniProt, with action and pharmacological action
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6Marketed productsAcross 1 country and 1 labeller
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7+ReferencesStructured and connected to the statements they support
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