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Phenylbutyric acid
go.drugbank.com/drugs/DB06819ApprovedInvestigationalPhenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria fermentation. … It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone.
Synonyms: 4-Phenyl-n-butyric acid, γ-Phenyl-n-butyric acidVarespladib methyl
go.drugbank.com/drugs/DB05737InvestigationalVarespladib methyl has been investigated for the treatment of Acute Coronary Syndrome. … Studies showed that Varespladib methyl treatment resulted in significant positive changes on lipoproteins and inflammation.
ETC-588
go.drugbank.com/drugs/DB05456ExperimentalEsperion is currently developing ETC-588 as a treatment for patients with acute coronary syndromes. … ETC-588, or LUV (large unilamellar vesicles), is made of naturally occurring lipids that circulate through arteries to facilitate the role of high-density lipoprotein (HDL) in removing accumulated cholesterol
Pindolol
go.drugbank.com/drugs/DB00960ApprovedInvestigationalPindolol is a first generation non-selective beta blocker used in the treatment of hypertension. … [A231059] Research into pindolol's use in the treatment of hypertension began in the early 1970s.[A231064] Pindolol was granted FDA approval on 3 September 1982.[L32348]
Categories: Antihypertensive Agents Indicated for HypertensionInternational brands: Blockin L, Blocklin LThioproperazine
go.drugbank.com/drugs/DB01622ApprovedThioproperazine is a potent neuroleptic with antipsychotic properties. … It is used for the treatment of all types of acute and chronic schizophrenia, including those which did not respond to the usual neuroleptics; manic syndromes.
Synonyms: N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine-2-sulfonamide, N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine-2-sulfonamideTirofiban
go.drugbank.com/drugs/DB00775ApprovedInvestigationalTirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. … It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Synonyms: N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosineProducts: AGGRASTAT CONCENTRATE FOR INFUSION 0.25 mg/ml, AGGRASTAT 0.25mg/ml CONCENTRATE FOR INFUSIONTTP889
go.drugbank.com/drugs/DB05131InvestigationalTTP889, an orally bioavailable selective inhibitor of the intrinsic coagulation pathway, is being developed as an anticoagulant for the treatment of thromboembolic disorders. … TTP889 is the only known selective small molecule inhibitor of Factor IX, a key enzyme of the intrinsic pathway of the blood coagulation system.
Mupadolimab
go.drugbank.com/drugs/DB16488InvestigationalNCT04464395 and NCT04734873 assessed its use for hospitalized COVID-19 patients alone or with standard care. … NCT03454451 focused on advanced cancers (e.g., non-small cell lung cancer, renal cell cancer, colorectal cancer).
Categories: Experimental Unapproved Treatments for COVID-19Aspergillus flavus
go.drugbank.com/drugs/DB10694ApprovedAspergillus flavus is a fungus which can provoke allergic reactions. Aspergillus flavus extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold MixtureCopper Cu-64
go.drugbank.com/drugs/DB13980ApprovedCopper-64 is a radiopharmaceutical usually found in the +2 oxidation state as the complexes including the +1 state tend to be more unstable. … [T604] It is used in molecular radiotherapy and positron emission tomography.
Mixtures: Dermamed Nutrition for troubled skin