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Displaying results 3341 - 3350 of 10000 in total
  1. Drug

    Polyvinyl alcohol

    go.drugbank.com/drugs/DB11060
    Approved

    Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol. … Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes [L2826].

    Mixtures: Leader Artificial Tears 15 mL, SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 MLCategories: Compounds used in a research, industrial, or household setting
  2. Drug

    Manidipine

    go.drugbank.com/drugs/DB09238
    ApprovedInvestigationalWithdrawn

    Manidipine (INN) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive.

    Mixtures: VIVACE 30/10MG TABLETTEN, VIVACE 30/10MG TABLETTENCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Inhibitors
  3. Drug

    Cobimetinib

    go.drugbank.com/drugs/DB05239
    ApprovedInvestigational

    Cobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: COTELLIC® (COBIMETINIB) 20 MG TABLETAS RECUBIERTAS, COTELLIC FILM-COATED TABLET 20 MG
  4. Drug

    Valbenazine

    go.drugbank.com/drugs/DB11915
    ApprovedInvestigational

    The reduction in chorea severity was observed as early as 2 weeks after starting treatment with an initial dose of 40 mg.[L47910] … This approval was supported by positive results in multiple trials, including the KINECT-HD Phase 3 study and the ongoing KINECT-HD2 open-label extension trial.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: REMLEAS HARD CAPSULES 40 MG, REMLEAS™ hard capsules 40mg
  5. Drug

    Calcium citrate

    go.drugbank.com/drugs/DB11093
    ApprovedInvestigational

    Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements.

    Mixtures: CALCIBON D® 315 MG, Cal-mag With Vitamin DCategories: ascorbic acid (vit C) and calcium, Compounds used in a research, industrial, or household setting
  6. Drug

    Sodium iodide

    go.drugbank.com/drugs/DB11119
    ApprovedInvestigational

    Sodium iodide is a water-soluble ionic compound with a crystal lattice. … Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition [L2065] but is more commonly used in veterinary medicine.

    Mixtures: FERTOMCIDINA U, FERTOMCIDINA UProducts: TAEK-PHT 123I-NAI (SODYUM İYODÜR) 37 MBQ/ML I.V. ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET, Sodium Iodide Inj 100mg/ml
  7. Drug

    Cendakimab

    go.drugbank.com/drugs/DB18427
    Investigational

    Cendakimab is a recombinant humanized anti-interleukin 13 (IL-13) monoclonal antibody.

    Synonyms: IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS IL-13 (INTERLEUKIN 13, IL-13)), HUMANIZED MONOCLONAL ANTIBODYGAMMA1 HEAVY CHAIN HUMANIZED (1-453) (VH (HOMO SAPIENS IGHV2-5*08 (80.6%) -(IGHD) -IGHJ4*01 (100%, )) (10.7.15) (1-123) -HOMO SAPIENS IGHG1*03V, G1M3>G
  8. Drug

    Phytochlorin

    go.drugbank.com/drugs/DB19265
    Investigational

    Phytochlorin is under investigation in clinical trial NCT06311890 (Study to Evaluate the Efficacy, Safety and Tolerability of Photodynamic Therapy(pdt) With Chlorin-e6 in Treating Moderate to Severe Acne).

    Synonyms: 21h,23h-porphine-7-propanoic acid, 3-carboxy-5-(carboxymethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17-tetramethyl-, (7s,8s)-, 2-porphinepropionic acid, 18-carboxy-20-(carboxymethyl)-13-ethyl-2.beta.,3-dihydro-3.beta.,7,12,17-tetramethyl-8-vinyl-Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More Rings
  9. Drug

    Pergolide

    go.drugbank.com/drugs/DB01186
    ApprovedVet approvedWithdrawn

    It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine (5-HT) receptors. … Pergolide is a long-acting dopamine agonist approved in 1982 for the treatment of Parkinson’s Disease.

    Categories: Serotonin 5-HT2 Receptor Agonists, Cytochrome P-450 CYP3A InhibitorsProducts: PERGOLID-NEURAX 1 MG, PERGOLID-NEURAX 0.25 MG
  10. Drug

    Ethionamide

    go.drugbank.com/drugs/DB00609
    ApprovedInvestigationalWithdrawn

    A second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-ethyl-4-thiopyridylamide, 2-ethylthioisonicotinamide