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Displaying results 3341 - 3350 of 10000 in total
  1. Drug

    Busulfan

    go.drugbank.com/drugs/DB01008
    ApprovedInvestigational

    According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen. … It is not a structural analog of the nitrogen mustards.

  2. Drug

    Aripiprazole

    go.drugbank.com/drugs/DB01238
    ApprovedInvestigational

    Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin Receptor AgonistsProducts: ARIPIPRAZOL PUR 1MG/ML LOE
  3. Drug

    Cenobamate

    go.drugbank.com/drugs/DB06119
    ApprovedInvestigational

    [A188442,L10653] The exact mechanism of action has not been described in the literature, though it positively modulates GABA<sub>A</sub> and inhibits voltage gated sodium channels. … Cenobamate, or YKP-3089, is an antiepileptic drug developed by SK Pharmaceuticals and used to treat partial onset seizures.

  4. Drug

    Metandienone

    go.drugbank.com/drugs/DB13586
    ApprovedWithdrawn

    It was introduced to the market in the 1960s but later discontinued and withdrawn from the market. … [A254432] In the US, metandienone is a controlled substance under the Controlled Substances Act.[L44057]

  5. Drug

    AV608

    go.drugbank.com/drugs/DB05072
    Investigational

    It is developed for the treatment of Social anxiety disorder (SAD), irritable bowel syndrome (IBS) and overactive bladder (OAB).

  6. Drug

    Avapritinib

    go.drugbank.com/drugs/DB15233
    ApprovedInvestigational

    Avapritinib, or BLU-285,[A189327] is a selective tyrosine kinase inhibitor of KIT and platelet derived growth factor receptor alpha indicated for the treatment of unresectable, metastatic gastrointestinal … [A189339,L40363] It is one of the first medications available for the treatment of multidrug resistant cancers.[A189327] Avapritinib shares a similar mechanism with [ripretinib].

  7. Target

    Integrin beta-7

    go.drugbank.com/bio_entities/BE0003414
    TargetHumans

    Integrin ITGAE/ITGB7 (alpha-E/beta-7, HML-1) is a receptor for E-cadherin (PubMed:10837471) … Integrin ITGA4/ITGB7 (alpha-4/beta-7) (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT) (Probable

    Synonyms: Gut homing receptor beta subunit
  8. Drug

    Inulin

    go.drugbank.com/drugs/DB00638
    ApprovedInvestigationalNutraceutical

    A starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan. … It has been used in physiologic investigation for determination of the rate of glomerular function.

  9. Drug

    Scorpion (centruroides) immune Fab2 antivenin (equine)

    go.drugbank.com/drugs/DB13905
    Approved

    It is the first specific treatment to neutralize toxin from Centruroides scorpion stings, particularly those of the _Centruroides sculpturatus_ in the United States [L2206]. … It is intravenously administered patients with clinical signs of scorpion envenomation so that the Fab fragments bind to the toxins and limit systemic toxicity.

    Products: ALVENO AC 10 ML IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET FLAKON+1 ADET ÇÖZÜCÜ AMPUL
  10. Drug

    Anisindione

    go.drugbank.com/drugs/DB01125
    Approved

    II, VII, IX, and X, as well as the anticoagulant proteins C and S, in the liver. … Its anticoagulant action is mediated through the inhibition of the vitamin K-mediated gamma-carboxylation of precursor proteins that are critical in forming the formation of active procoagulation factors