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Anti-SARS-CoV-2 REGN-COV2
go.drugbank.com/drugs/DB15691InvestigationalThis drug is a combination of the antibodies REGN10933 and REGN10987, derived from humanized VelocImmune® mice in addition to blood samples from patients who have recovered from COVID-19. … These antibodies have been formulated to bind to multiple locations on the SARS-COV-2 spike protein, preventing viral escape.
Ergosterol
go.drugbank.com/drugs/DB04038ApprovedWithdrawnA steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result
Panax notoginseng root
go.drugbank.com/drugs/DB14304InvestigationalPanax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mixtures: GONGFUTOUTANG Tou Tang Powder No. 3Eslicarbazepine acetate
go.drugbank.com/drugs/DB09119ApprovedInvestigationalEslicarbazepine acetate is a prodrug that is rapidly converted to eslicarbazepine, the primary active metabolite in the body. … but it is known that it does exert anticonvulsant activity by inhibiting repeated neuronal firing and stabilizing the inactivated state of voltage-gated sodium channels, thus preventing their return to
Opicapone
go.drugbank.com/drugs/DB11632ApprovedInvestigationalExhibiting a long duration of action that exceeds 24 hours, opicapone can be administered once-daily [L2336] and demonstrates the lowest risk for cytotoxicity compared to other catechol-O-methyltransferase … [L2336] Opicapone is used for adjunct therapy to levodopa and carbidopa in adult patients with Parkinson's disease and end-of-dose motor fluctuations.
Centanafadine
go.drugbank.com/drugs/DB14841ApprovedInvestigationalCentanafadine is a reuptake inhibitor at the norepinephrine, dopamine, and serotonin transporters and a central nervous system stimulant. Its mechanism in ADHD is unclear, but its efficacy may be mediated by this triple reuptake inhibiti...
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeDextroamphetamine
go.drugbank.com/drugs/DB01576ApprovedIllicitInvestigationalDextroamphetamine is the dextrorotatory enantiomer of amphetamine . Dextroamphetamine was approved by the FDA in 2001 for the treatment of attention deficit hyperactivity disorder.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeG207
go.drugbank.com/drugs/DB05827InvestigationalG207 is cancer-killing viruses, so-called oncolytic viruses, for the treatment of various forms of cancer developed by MediGene AG. … MediGene uses these viruses, however, in a modified and "disarmed" form in order to make them utilizable as a therapeutic agent in humans.
Indocyanine green acid form
go.drugbank.com/drugs/DB09374ApprovedInvestigationalEach vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.