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Thyroxine 5-deiodinase
go.drugbank.com/bio_entities/BE0009333TargetEnzymeHumansT1), rT3 to 3',5'-diiodothyronine (3',5'-T2) and 3,3'-T2 to 3'-monoiodothyronine (3'-T1) via inner-ring deiodination (IRD) (PubMed:7593630, PubMed:12586771, PubMed:12746313, PubMed:18821722, PubMed:18339710 … Catalyzes the deiodination of L-thyroxine (T4) to 3,3',5'-triiodothyronine (rT3), 3,5,3'-triiodothyronine (T3) to 3,3'-diiodothyronine (3,3'-T2), 3,5-diiodothyronine (3,5-T2) to 3-monoiodothyronine (3-
Polypeptides: Thyroxine 5-deiodinaseFunction: thyroxine 5'-deiodinase activityPseudouridine-5'-phosphatase
go.drugbank.com/bio_entities/BE0014361EnzymeHumansDephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine
Polypeptides: Pseudouridine-5'-phosphataseSynonyms: 5'-PsiMPase, Pseudouridine-5'-monophosphataseNADPH oxidase 5
go.drugbank.com/bio_entities/BE0018640TargetHumansCalcium-dependent NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor (PubMed:12686516). Also synthesizes NAADP from its reduced NAADPH form which promotes Ca(2+) signaling...
Polypeptides: NADPH oxidase 5Bezafibrate
go.drugbank.com/drugs/DB01393ApprovedInvestigationalAntilipemic agent that lowers cholesterol and triglycerides. It decreases low density lipoproteins and increases high density lipoproteins.
Categories: Benzamides and benzamide derivatives, Cytochrome P-450 SubstratesSynonyms: 2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acidCamphor 5-monooxygenase
go.drugbank.com/bio_entities/BE0001246TargetPseudomonas putidaInvolved in a camphor oxidation system.
Polypeptides: Camphor 5-monooxygenaseFunction: camphor 5-monooxygenase activityDaclatasvir
go.drugbank.com/drugs/DB09102ApprovedInvestigationalWithdrawnDaclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection. … Daclatasvir was FDA-approved in July 2015 for use with [DB08934] (Sovaldi) with or without [DB00811] to treat HCV genotype 1 and 3 infections.
Categories: Heterocyclic Compounds, 1-Ring, Amino Acids, Peptides, and ProteinsProducts: DASVIR 30 (DACLATASVIR TABLETS 30 MG), DASVIR 60 (DACLATASVIR TABLETS 60 MG)Xylitol
go.drugbank.com/drugs/DB11195ApprovedInvestigationalThe recommended dose of xylitol for dental caries prevention is 6–10 g/day, and most adults can tolerate 40 g/day without adverse events [A22081]. … It is widely used as a sugar substitute and in "sugar-free" food products.
Mixtures: Fluor-a-day, Fluor-a-dayCategories: Diet, Food, and Nutrition, Compounds used in a research, industrial, or household settingBenznidazole
go.drugbank.com/drugs/DB11989ApprovedInvestigationalBenznidazole was granted accelerated approval for the treatment of Chagas disease in children 2-12 years of age by the FDA on August 29, 2017.
Categories: Heterocyclic Compounds, 1-Ring, Agents Against Leishmaniasis and TrypanosomiasisProducts: ABALEA ®100 MGBenzonatate
go.drugbank.com/drugs/DB00868Approved[L11193] Although it not prone to drug misuse or abuse, benzonatate is associated with a risk for severe toxicity and overdose, especially in children.[A189513] … [A5790] Currently, benzonatate is the only non-narcotic antitussive available as a prescription drug.
Categories: Cough and Cold PreparationsSynonyms: 4-(butylamino)benzoic acid 3,6,9,12,15,18,21,24,27-nonaoxaoctacos-1-yl ester, 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-butylaminobenzoateSafinamide
go.drugbank.com/drugs/DB06654ApprovedInvestigationalIt was approved in Europe in February 2015, and in the United States on March 21, 2017.
Categories: Amino Acids, Peptides, and Proteins, Cytochrome P-450 SubstratesProducts: Equfina Film coated Tablets 50 mg, XADAGO 50 MG TABLETAS RECUBIERTAS CON PELÍCULA