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Displaying results 3361 - 3370 of 3917 in total
  1. Drug

    Nitroxoline

    go.drugbank.com/drugs/DB01422
    Experimental

    Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. It is a hydroxyquinoline derivative unrelated to other classes of drugs. Nitrox...

  2. Drug

    Ledipasvir

    go.drugbank.com/drugs/DB09027
    Approved

    More specifically, ledipasvir is an inhibitor of the Hepatitis C Virus (HCV) Non-Structural Protein 5A (NS5A), which is required for viral RNA replication and assembly of HCV virions. … Approved in October 2014 by the FDA, Harvoni is indicated for the treatment of HCV genotypes 1, 4, 5, and 6 with or without [ribavirin] depending on the level of liver damage or cirrhosis [FDA Label].

  3. Drug

    AT-GTX-502

    go.drugbank.com/drugs/DB17001
    Experimental

    AT-GTX-502 is an experimental, one-time gene therapy that uses AAV9 to deliver a functional copy of CLN3.

    Categories: Non-Replicating Recombinant, Self-Complementary Adeno-Associated Virus Serotype 9 Containing the Human CLN3 Gene
  4. Drug

    Zofenopril

    go.drugbank.com/drugs/DB13166
    ApprovedInvestigational

    Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.

    Categories: Agents Acting on the Renin-Angiotensin System
  5. Drug

    Mofezolac

    go.drugbank.com/drugs/DB21153
    Experimental

    Mofezolac is a small molecule drug. The usage of the INN stem '-ac' in the name indicates that Mofezolac is a anti-inflammatory agent, ibufenac derivative. Mofezolac has a monoisotopic molecular weight of 339.11 Da.

    Categories: Analgesics, Non-Narcotic, Anti-Inflammatory Agents, Non-Steroidal
  6. Drug

    Lawsonia inermis leaf

    go.drugbank.com/drugs/DB14313
    Investigational

    Lawsonia inermis leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Categories: Non-Standardized Plant Allergenic Extract
  7. Drug

    Dextromethadone

    go.drugbank.com/drugs/DB15198
    Investigational

    Dextromethadone is under investigation in clinical trial NCT00588640 (Study of D-Methadone in Patients With Chronic Pain).

    Categories: Analgesics, Non-Narcotic
  8. Drug

    GFT14

    go.drugbank.com/drugs/DB05061
    Experimental

    ) and on other risk factors such as hypertension or diabetes. … GFT14 is destined to improve the condition of patients at risk from cardiovascular disease by a simultaneous and favorable action on the plasmatic lipids (rise of HDL- cholesterol et lowering of triglycerides

  9. Drug

    Zileuton

    go.drugbank.com/drugs/DB00744
    ApprovedWithdrawn

    Leukotrienes are substances that induce numerous biological effects including augmentation of neutrophil and eosinophil migration, neutrophil and monocyte aggregation, leukocyte adhesion, increased capillary permeability, and smooth musc...

    Categories: Analgesics, Non-Narcotic
  10. Drug

    Ambrisentan

    go.drugbank.com/drugs/DB06403
    ApprovedInvestigational

    Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. It is approved in Europe, Canada and the United States for use as a single agent to improve e...