Dextromethadone

DB15198InvestigationalSmall molecule

Dextromethadone is under investigation in clinical trial NCT00588640 (Study of D-Methadone in Patients With Chronic Pain).

Chemical structure of Dextromethadone
Mechanism
Curator reviewed
Formula / weight
C21H27NO · 309.453 g/mol (avg)
Also known as
D-methadone · Esmethadone
Code names
REL-1017

Resolves to

Compound
UNIIS95RZH8AMHCAS5653-80-5ChEMBLCHEMBL350719ChEBI167308
Structure
InChIKeyUSSIQXCVUWKGNF-KRWDZBQOSA-NSMILESCCC(=O)C(C[C@H](C)N(C)C)(C1=CC=CC=C1)C1=CC=CC=C1
Targets
P35372OPRM1P48549KCNJ3

What you can answer from here — as of September 13, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
8Clinical trialsPhase, status and sponsor resolved per trial
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17+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Dextromethadone, and which of those have an active Phase 3 trial?

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