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2,4-thiazolidinedione
go.drugbank.com/drugs/DB11898InvestigationalThiazolidinedione has been investigated for the treatment of Type 2 Diabetes, Diabetes Mellitus, and DIABETES MELLITUS, TYPE 2.
Categories: Heterocyclic Compounds, 1-RingTimapiprant
go.drugbank.com/drugs/DB11900InvestigationalOC000459 is under investigation for the treatment of Severe Eosinophilic Asthma. OC000459 has been investigated for the treatment of Bronchial Asthma.
Categories: Heterocyclic Compounds, 2-RingApalutamide
go.drugbank.com/drugs/DB11901ApprovedInvestigationalIt is available as oral tablets. Apalutamide is the first FDA-approved treatment for non-metastatic, castration-resistant prostate cancer [L1295]. … Apalutamide is a potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and blocks AR nuclear translocation or binding to androgen response elements [A31846]
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsProducts: ERLEADA ®TABLETAS RECUBIERTAS 60 MGRociletinib
go.drugbank.com/drugs/DB11907InvestigationalRociletinib has been used in trials studying the treatment and prevention of Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer.
Categories: Heterocyclic Compounds, 1-RingLebrikizumab
go.drugbank.com/drugs/DB11914ApprovedInvestigationalThis approval is based on the positive results obtained from the Phase 3 studies ADvocate 1 and ADvocate 2, where nearly 80% of patients taking lebrikizumab either as monotherapy or combination therapy … Lebrikizumab is a monoclonal antibody that binds to IL-13 with high affinity and slow off-rate.[L51374] It binds to a different epitope compared [tralokinumab].
Indium In-111
go.drugbank.com/drugs/DB11916InvestigationalIndium In-111 is under investigation in clinical trial NCT00493454 (Ibritumomab Tiuxetan for Treatment of Non-Follicular CD20+ Indolent Lymphomas).
Guadecitabine
go.drugbank.com/drugs/DB11918InvestigationalGuadecitabine is under investigation for the treatment of Previously Treated Metastatic Colorectal Cancer.
Categories: Heterocyclic Compounds, 1-Ring6-O-benzylguanine
go.drugbank.com/drugs/DB11919Investigational6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: O(6)-BenzylguanineLesogaberan
go.drugbank.com/drugs/DB11920InvestigationalLesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn, Regurgitation, and Reflux Disease, among others.
Categories: GABA-A Receptor AgonistsEpelsiban
go.drugbank.com/drugs/DB11934InvestigationalEpelsiban has been investigated for the treatment of Premature Ejaculation.
Categories: Heterocyclic Compounds, 1-Ring