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Displaying results 3371 - 3380 of 10000 in total
  1. Drug

    Tarlatamab

    go.drugbank.com/drugs/DB17256
    ApprovedInvestigational

    Tarlatamab is a first-in-class T-cell engager used to treat extensive-stage small cell lung cancer. … T-cell engager to receive marketing approval.

    Synonyms: Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chain (scfv)2-scfc, bispecific
  2. Drug

    Capivasertib

    go.drugbank.com/drugs/DB12218
    ApprovedInvestigational

    metastatic breast cancer with one or more alterations in PIK3CA/AKT1/PTEN gene(s) in combination with [fulvestrant]. … Therefore, targeting the PIK3/AKT pathway presents a promising approach for the treatment of breast cancer, leading to the development of capivasertib, a pan-AKT kinase inhibitor.

    Categories: MATE 1 Inhibitors, MATE 2 Inhibitors
  3. Drug

    Calcium glubionate anhydrous

    go.drugbank.com/drugs/DB13142
    Approved

    Calcium glubionate (or glubionate calcium) is a mineral supplement to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets.

    Synonyms: (D-gluconato)(lactobionato)calcium, Calcium D-gluconate lactobionateProducts: CALCIUM SANDOZ %10 AMPUL, 5 ADET, CALCIUM SANDOZ 10 ML 1,375 GR AMPUL, 5 ADET
  4. Indication

    Myalgia

    go.drugbank.com/conditions/DBCOND0002210
    Drugs: (+)-menthol · (S)-camphor · 2-(l-menthoxy)ethanol · Acetaminophen · Acetylsalicylic acid · Borneol +28 more
  5. Drug

    Proguanil

    go.drugbank.com/drugs/DB01131
    Approved

    Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, _Plasmodium falciparum_ and _Plasmodium vivax_, from reproducing once it is in the red blood cells. … It does this by inhibiting the enzyme, dihydrofolate reductase, which is involved in the reproduction of the parasite.

    Synonyms: 1-(p-Chlorophenyl)-5-isopropylbiguanideMixtures: ATOVAQUONE E PROGUANILE SANDOZ, ATOVAQUONE E PROGUANILE MYLAN GENERICS
  6. Drug

    Olaratumab

    go.drugbank.com/drugs/DB06043
    ApprovedInvestigational

    Olaratumab (IMC-3G3) is a fully human IgG1 monoclonal antibody with antitumor activity that selectively binds the external domain of human platelet-derived growth factor receptor (PDGFR)-α with high affinity … Olaratumab was granted accelerated approval (as Lartruvo) as initial therapy to treat adults with certain types of soft tissue sarcoma (STS) in October, 2016.

  7. Drug

    Medium-chain triglycerides

    go.drugbank.com/drugs/DB13959
    ApprovedInvestigational

    In the body, MCTs are broken down into glycerol and free fatty acids, which are directly absorbed into the blood stream and transported to the target organs to exert a range of biological and metabolic … Medium-chain triglycerides (MCTs) are triglycerides made up of a glycerol backbone and three fatty acids with an aliphatic tail of six to 12 carbon atoms.

    Mixtures: LIPOFUNDIN MCT/LCT %10 VIT E INFUZYON ICIN YAG EMULSUYONU, 100 ML, LIPOFUNDIN MCT/LCT %10 VIT E INFUZYON ICIN YAG EMULSUYONU, 250 ML
  8. Drug

    N-alkyl ethylbenzyl dimethyl ammonium (C12-C14)

    go.drugbank.com/drugs/DB11202
    Approved

    and exposure, although the formal mechanism of action of quaternary ammonium compounds like n-alkyl C12-C14 dimethyl ethylbenzyl ammonium chloride is difficult to elucidate. … It is found in sanitizing solutions or soaps as an active ingredient due to its antimicrobial properties.

    Salts: N-alkyl ethylbenzyl dimethyl ammonium chloride (C12-C14)Mixtures: E-2 Cleanser Sanitizer, All Star Antiseptic Hand Soap E-2
  9. Drug

    Berahyaluronidase alfa

    go.drugbank.com/drugs/DB22790
    ApprovedInvestigational

    Berahyaluronidase alfa is a recombinant variant of human hyaluronidase designed to enhance dispersion and permeation of subcutaneously co-administered drugs. … This combination was approved by the US FDA in September 2025 and is indicated for various solid tumors in adults and pediatric patients 12 years and older, offering a subcutaneous option for indications

  10. Drug

    Succinylcholine

    go.drugbank.com/drugs/DB00202
    ApprovedInvestigational

    Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter [acetylcholine] (ACh) linked by their acetyl groups. … Its rapid onset and offset, with effects beginning within 60 seconds of intravenous administration and lasting between four to six minutes, make succinylcholine particularly useful in the setting of short

    Synonyms: 2,2'-[(1,4-dioxobutane-1,4-diyl)bis(oxy)]bis(N,N,N-trimethylethanaminium)Products: Cloruro de suxametonio, Lysthenon 0,1 g/5 ml - Injektionslösung