This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Borneol
- DrugBank Accession Number
- DB11288
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Borneol (DB11288)
- Weight
- Average: 154.2493
Monoisotopic: 154.135765198 - Chemical Formula
- C10H18O
- Synonyms
- Borneo camphor
- Bornyl alcohol
- endo-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol
- endo-2-bornanol
- endo-2-camphanol
- endo-2-hydroxycamphane
- Sumatra camphor
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination for symptomatic treatment of Arthritis Combination Product in combination with: Methyl salicylate (DB09543), Camphor (DB01744), Thymol (DB02513), Levomenthol (DB00825) ••• ••• ••••••• Used in combination to treat Backache Combination Product in combination with: Levomenthol (DB00825), Camphor (DB01744), Thymol (DB02513), Methyl salicylate (DB09543) ••• ••• ••••••• Used in combination to treat Bruises Combination Product in combination with: Camphor (DB01744), Methyl salicylate (DB09543), Thymol (DB02513), Levomenthol (DB00825) ••• ••• ••••••• Used as adjunct in combination to treat Diabetes Combination Product in combination with: Eucalyptol (DB03852), Menthone (DB15920), Camphene (DB15917), Levomenthol (DB00825), alpha-Pinene (DB15573), beta-Pinene (DB15574) •••••••••••• ••••••• Used in combination to treat Gallbladder disorders Combination Product in combination with: Levomenthol (DB00825), alpha-Pinene (DB15573), beta-Pinene (DB15574), Camphene (DB15917), Menthone (DB15920), Eucalyptol (DB03852) •••••••••••• ••••••• - Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
Target Actions Organism ATransient receptor potential cation channel subfamily V member 3 activatorHumans - Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Cream Cream 3 g/20g Cutaneous Shantou Youjia E-Commerce Co., Ltd. 2024-02-01 2024-12-31 US 
Enokon Pain relief patch Patch 1 g/1001 Topical Henan Enokon Medical Instrument Co Ltd. 2023-06-28 Not applicable US Enokon Pain relief patch-acupoint pressure stimulation Patch 1 g/1001 Topical Henan Enokon Medical Instrument Co Ltd. 2023-01-06 Not applicable US Tendon Sheath Patch Patch 15 g/1001 Topical Guangzhou Hanhai Trading Co., Ltd 2023-09-19 Not applicable US Varicose Veins Patch Patch 12 g/1001 Topical Guangzhou Hanhai Trading Co., Ltd 2023-09-12 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Hundred Koyok Classic Borneol (0.18 mg) + Camphor (0.41 mg) + Levomenthol (0.62 mg) + Methyl salicylate (0.62 mg) + Thymol (0.04 mg) Plaster Transdermal JWP Medical Sdn. Bhd. 2020-09-08 Not applicable Malaysia 
HundredPlast Koyok Borneol (0.18 mg) + Camphor (0.41 mg) + Levomenthol (0.62 mg) + Methyl salicylate (0.62 mg) + Thymol (0.04 mg) Patch Topical TEONG HUAT MEDICAL SDN. BHD. 2020-09-08 Not applicable Malaysia HUNDREDPLAST KOYOK CLASSIC Borneol (1.5 %w/w) + Camphor (3 %w/w) + Levomenthol (6.5 %w/w) + Methyl salicylate (6.5 %w/w) + Thymol (0.5 %w/w) Plaster Transdermal THP MEDICAL SDN. BHD. 2020-09-08 Not applicable Malaysia Kwan Tak Hing Plaster - Pad-pls Borneol (1.75 g / pad) + Levomenthol (3.5 g / pad) Plaster; Swab Topical Wing Quon Enterprises Ltd. 1996-08-16 1998-08-12 Canada 
La Jiao Feng Shi Gao Borneol (3.0 g/100g) + Levomenthol (3.0 g/100g) Plaster Transdermal Henan Lingrui Pharmaceutical Co.; Ltd 2010-06-02 2014-03-11 US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Ma Ying Long Hemorrhoidal Borneol (0.2 g/10g) + Amber (0.1 g/10g) + Bos taurus gallstone (0.1 g/10g) + Moschus berezovskii musk sac resin (0.15 g/10g) + Pearl (hyriopsis cumingii) (0.25 g/10g) + Sodium borate decahydrate (0.2 g/10g) + Zinc carbonate (0.65 g/10g) Ointment Topical Trifecta Pharmaceuticals Usa, Llc. 2016-01-14 Not applicable US Tendon Sheath Patch Borneol (15 g/1001) Patch Topical Guangzhou Hanhai Trading Co., Ltd 2023-09-19 Not applicable US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- M89NIB437X
- CAS number
- 507-70-0
- InChI Key
- DTGKSKDOIYIVQL-UHFFFAOYSA-N
- InChI
- InChI=1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3
- IUPAC Name
- 1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol
- SMILES
- CC1(C)C2CCC1(C)C(O)C2
References
- General References
- Not Available
- External Links
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample data2 Completed Treatment Allergic Rhinitis (AR) / Nasal Lavage / Traditional Chinese Medicine 1 somestatus stop reason just information to hide 1 Unknown Status Treatment Intracranial Hemorrhages / Stroke, Acute 1 somestatus stop reason just information to hide 0 Completed Treatment Chronic Stable Angina Pectoris 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Cream Cutaneous 3 g/20g Patch Topical 1 g/1001 Patch Topical Plaster; swab Topical Plaster Transdermal Ointment Topical Dressing Cutaneous Capsule Oral Plaster Topical Spray Topical Plaster Patch Topical 15 g/1001 Capsule, gelatin coated Oral Patch Topical 12 g/1001 Ointment Liquid Dental Solution Oral Capsule - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.805 mg/mL ALOGPS logP 2.83 ALOGPS logP 1.99 Chemaxon logS -2.3 ALOGPS pKa (Strongest Acidic) 19.6 Chemaxon pKa (Strongest Basic) -0.78 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 20.23 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 45.31 m3·mol-1 Chemaxon Polarizability 18.48 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 140.85579 predictedDeepCCS 1.0 (2019) [M+H]+ 143.25136 predictedDeepCCS 1.0 (2019) [M+Na]+ 150.63554 predictedDeepCCS 1.0 (2019)
Targets
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- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Yes
- Actions
- Activator
- General Function
- Receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen)
- Specific Function
- Calcium channel activity
- Gene Name
- TRPV3
- Uniprot ID
- Q8NET8
- Uniprot Name
- Transient receptor potential cation channel subfamily V member 3
- Molecular Weight
- 90635.115 Da
References
- Zhou Y, Zhang Y, Zhao D, Yu X, Shen X, Zhou Y, Wang S, Qiu Y, Chen Y, Zhu F: TTD: Therapeutic Target Database describing target druggability information. Nucleic Acids Res. 2024 Jan 5;52(D1):D1465-D1477. doi: 10.1093/nar/gkad751. [Article]
Drug created at December 03, 2015 16:52 / Updated at August 26, 2024 19:21