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Curcuma aromatica root oil
go.drugbank.com/drugs/DB11301ApprovedThe major constituents of Curcuma aromatica root oil are reported to be camphor, curzerenone, α-turmerone, ar-turmerone and 1,8-cineole [A27219]. … Curcuma aromatica root oil is obtained from the roots of *Curcuma aromatica*, or more commonly called wild tumeric, via steamed distillation. *Curcuma aromatica* belongs to the family Zingiberaceae.
Atovaquone
go.drugbank.com/drugs/DB01117ApprovedInvestigationalAtovaquone is a hydroxynaphthoquinone, or an analog of ubiquinone, that has antimicrobial and antipneumocystis activity. It is being used in antimalarial protocols.
Mixtures: ATOVAQUONE E PROGUANILE SANDOZ, ATOVAQUONE E PROGUANILE MYLAN GENERICSProducts: ATOVAQUONE E PROGUANILE SANDOZEquine Botulinum Neurotoxin B Immune FAB2
go.drugbank.com/drugs/DB13903ApprovedIt is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes B in adults and pediatric patients.
Durvalumab
go.drugbank.com/drugs/DB11714ApprovedInvestigationalIt was granted accelerated approval by the FDA in May 2017 [A192807] for the treatment of selected patients with locally advanced or metastatic urothelial carcinoma. … [L12621] In September 2018, durvalumab was approved by the EMA for the treatment of adult patients with locally advanced, unresectable non-small cell lung cancer (NSCLC), only if PD-L1 is expressed in
Equine Botulinum Neurotoxin E Immune FAB2
go.drugbank.com/drugs/DB13897ApprovedIt is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes E in adults and pediatric patients. … Equine Botulinum Neurotoxin E Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype E.
Synonyms: Botulinum Neurotoxin E immune FAB2 (equine), BOTULINUM NEUROTOXIN E IMMUNE FAB2, EQUINEEquine Botulinum Neurotoxin C Immune FAB2
go.drugbank.com/drugs/DB13898ApprovedIt is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes C in adults and pediatric patients.
Vismodegib
go.drugbank.com/drugs/DB08828ApprovedInvestigationalVismodegib is an orally active small molecule that inhibits the hedgehog signaling pathway by binding to and inhibiting the transmembrane protein smoothened homologue (SMO). … The Hedgehog signaling pathway plays an important role in the development of organs and tissues during embryogenesis.
Categories: Smoothened Receptor AntagonistsGuanylyl cyclase C
go.drugbank.com/bio_entities/BE0003502TargetHumansReceptor for the E.coli heat-stable enterotoxin; E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C (PubMed:1680854, PubMed:1718270).
Synonyms: STA receptor, Heat-stable enterotoxin receptorProhibitin-2
go.drugbank.com/bio_entities/BE0009007TargetHumansProtein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcrip...
Synonyms: B-cell receptor-associated protein BAP37, Repressor of estrogen receptor activityPhenylbutazone
go.drugbank.com/drugs/DB00812ApprovedVet approvedWithdrawnIt is especially effective in the treatment of ankylosing spondylitis. It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication). … Although phenylbutazone is effective in gouty arthritis, risk/benefit considerations indicate that this drug should not be employed for this disease. (From AMA Drug Evaluations Annual, 1994, p1822)