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Displaying results 3381 - 3390 of 10000 in total
  1. Drug

    XEN-D0101

    go.drugbank.com/drugs/DB06020
    Experimental

    XEN-D0101 is an investigational drug developed by Xention Inc. for the treatment of Atrial Fibrillation. XEN-D0101 works by being a selective antagonist of the voltage-gated potassium channel Kv1.5.

  2. Drug

    Ecraprost

    go.drugbank.com/drugs/DB16148
    Investigational

    Ecraprost is under investigation in clinical trial NCT00059657 (Efficacy/safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease).

  3. Drug

    Drotrecogin alfa

    go.drugbank.com/drugs/DB00055
    ApprovedWithdrawn

    Drotrecogin alfa was withdrawn from the market after a major study indicated that it was not effective in improving outcomes in patients with sepsis.

  4. Drug

    Macimorelin

    go.drugbank.com/drugs/DB13074
    Approved

    In clinical studies involving healthy subjects, macimorelin stimulated GH release in a dose-dependent manner with good tolerability [A31481]. … In deficiency of this hormone, AGHD is commonly associated with increased fat mass (particularly in the abdominal region), decreased lean body mass, osteopenia, dyslipidemia, insulin resistance, and/or

  5. Drug

    Denifanstat

    go.drugbank.com/drugs/DB17576
    Investigational

    Denifanstat is an orally bioavailable fatty acid synthase (FASN) inhibitor. Due to its antineoplastic activities, it is being investigated for various cancers.

  6. Drug

    Landiolol

    go.drugbank.com/drugs/DB12212
    ApprovedInvestigational

    [A264733,A264738] First approved in Japan in 2002 [A264758] for the treatment of intraoperative tachyarrhythmias,[A264733] landiolol was approved in Canada in April 2024 [L51938] and in the US in November … [A264733] Compared to other beta-blockers, landiolol possesses unique pharmacodynamic and pharmacokinetic properties, in that it has a rapid onset and short duration of action, and has a greater affinity

  7. Drug

    Estradiol dienanthate

    go.drugbank.com/drugs/DB13955
    ApprovedVet approvedWithdrawn

    in various tissues including in the breasts, uterus, ovaries, skin, prostate, bone, fat, and brain. … Estradiol dienanthate is not currently available in any commercially available products in Canada or the US.

  8. Drug

    Carboxin

    go.drugbank.com/drugs/DB04657
    ApprovedWithdrawn

    A systemic agricultural fungicide and seed treatment agent.

    Synonyms: 5,6-Dihydro-2-methyl-N-phenyl-1,4-oxathiin-3-carboxamideCategories: Compounds used in a research, industrial, or household setting
  9. Drug

    Perflenapent

    go.drugbank.com/drugs/DB11625
    ApprovedInvestigationalWithdrawn

    Dodecafluoropentane is also known as perfluoropentane or perflenapent.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Trypsin

    go.drugbank.com/drugs/DB11237
    ApprovedInvestigationalVet approved

    Trypsin is a serine protease that plays an essential role in protein hydrolysis and absorption in mammals. … When converted from its zymogen trypsinogen, trypsin is available as an active peptide hydrolase (EC 3.4.21.4) form to cleave peptide chains, mainly at the carboxyl side of the amino acids lysine or arginine