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Timolol
go.drugbank.com/drugs/DB00373ApprovedInvestigational[L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978. … Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes.
Mixtures: Xalacom 50 Mikrogramm/ml + 5 mg/ml Augentropfen, LatanoTim-Vision 50 Mikrogramm/ml + 5 mg/ml AugentropfenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesIrinotecan
go.drugbank.com/drugs/DB00762ApprovedInvestigationalBoth irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking its enzymatic activity, thereby interfering with DNA synthesis. … [L50181, L50186, L50201] Irinotecan liposome was approved by the FDA in February 2024.[L50186] The active metabolite SN-38 is also a potent inhibitor of DNA topoisomerase I.
Synonyms: (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 4-(2-(5-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-hydroxy-4H-1,2,4-triazol-4-yl)-1H-indol-1-yl, )ethyl)piperidine-1-carboxylateCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsMoxifloxacin
go.drugbank.com/drugs/DB00218ApprovedInvestigationalMoxifloxacin is a synthetic fluoroquinolone antibiotic agent. … Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Synonyms: 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acidMixtures: Ixoba M, Dex-MoxiAmantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalAn antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia.
Synonyms: 1-adamantanamine, 1-adamantylamineMixtures: Osmolex ER, Osmolex ERLanthanum carbonate
go.drugbank.com/drugs/DB06792ApprovedLanthanum carbonate is a phosphate binder marketed under the trade name _Fosrenol_ by Shire Pharmaceuticals. … It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects.
Synonyms: Lanthanum(3+) carbonateProducts: Fosrenol 250 mg Kautabletten, FOSRENOL 500 MGPropylthiouracil
go.drugbank.com/drugs/DB00550Approved(From Martindale, The Extra Pharmacopeoia, 30th ed, p534) … A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine.
Categories: Sex Hormones and Insulins, Heterocyclic Compounds, 1-RingSynonyms: 2-Mercapto-6-propyl-4-pyrimidone, 2-Mercapto-6-propylpyrimid-4-oneMemantine
go.drugbank.com/drugs/DB01043ApprovedInvestigationalAlmost doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and to 115 million by 2050 [F4366]. … Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD).
Mixtures: MEGINGO 20/50 MG EFERVESAN TABLET, 100 ADET, EVERON 90/5 MG FILM KAPLI TABLET ,50 TABLETCategories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP2B6 InhibitorsErdosteine
go.drugbank.com/drugs/DB05057ApprovedInvestigationalErdosteine is a drug that causes a breakdown of mucus, also known as a _mucolytic_ agent. … Erdosteine is associated with a low incidence of adverse events, most of which are gastrointestinal and generally mild.
Categories: Heterocyclic Compounds, 1-RingProducts: ENZEVİN 175 MG/5 ML SUSPANSIYON ICIN KURU TOZ, 200 ML, EVOSTEN 175 MG/5 ML ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 200 MLMirabegron
go.drugbank.com/drugs/DB08893ApprovedInvestigational[L32853] Mirabegron is also used in other jurisdictions across the globe, including Canada,[L32925] the EU,[L32945] and Japan.[A7469] … Mirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of the bladder in the treatment of urinary frequency and incontinence.
Categories: Genito Urinary System and Sex Hormones, Cytochrome P-450 SubstratesProducts: MYRBETRIC® 50 MG TABLETAS DE LIBERACION PROLONGADA, MYRBETRIC® 25 MG TABLETAS DE LIBERACION PROLONGADABupivacaine
go.drugbank.com/drugs/DB00297ApprovedInvestigationalBupivacaine is a widely used local anesthetic agent.
Synonyms: 1-Butyl-2',6'-pipecoloxylidide, dl-1-Butyl-2',6'-pipecoloxylidideMixtures: BUVACAINA® PESADA SOLUCION INYECTABLE 20 MG/ 4 ML, Physicians EZ Use M-pred