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Displaying results 331 - 340 of 688 in total
  1. Target

    Copper-transporting ATPase 2

    go.drugbank.com/bio_entities/BE0003664
    TransporterHumans

    Copper ion transmembrane transporter involved in the export of copper out of the cells. … It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload

    Polypeptides: Copper-transporting ATPase 2Synonyms: Copper pump 2
  2. Target

    CMV DNA Terminase Complex

    go.drugbank.com/bio_entities/BE0010221
    TargetHuman Cytomegalovirus

    Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. … Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.

  3. Drug

    Hexapeptide-2

    go.drugbank.com/drugs/DB18238
    Experimental

    Synonyms: His-d-trp-ala-trp-d-phe-lys nh2, His-d-trp-ala-trp-d-phe-lys-nh2
  4. Drug

    Redasemtide

    go.drugbank.com/drugs/DB19121
    Investigational

    Redasemtide is under investigation in clinical trial NCT05953480 (A Phase 2b, Randomized, Double-blind Study of Redasemtide (S-005151) in Adult Participants With Acute Ischemic Stroke).

    Synonyms: Met-gly-lys-gly-asp-pro-lys-lys-pro-arg-gly-lys-met-ser-ser-tyr-ala-phe-phe-val-gln-thr-cys-arg-glu-glu-his-lys-lys-lys-his-pro-asp-ala-ser-val-asn-phe-ser-glu-phe-ser-lys-lys
  5. Indication

    Primary Immune Complex Mediated Membranoproliferative Glomerulonephritis

    go.drugbank.com/conditions/DBCOND0173486
    Drugs: Pegcetacoplan
    Synonyms: Primary Immune Complex Mediated Membranoproliferative Glomerulonephritis
  6. Target

    Diamine oxidase [copper-containing]

    go.drugbank.com/bio_entities/BE0004667
    EnzymePig

    Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia (PubMed:1457410, PubMed:8144586). Its preferred substrates in vitro are the diamines hi...

    Polypeptides: Diamine oxidase [copper-containing]Synonyms: Amine oxidase copper domain-containing protein 1, Amiloride-sensitive amine oxidase [copper-containing]
  7. Drug

    DADLE

    go.drugbank.com/drugs/DB08856
    Experimental

    A delta-selective opioid (ANALGESICS, OPIOID). It can cause transient depression of mean arterial blood pressure and heart rate.

    Synonyms: H-Tyr-D-Ala-Gly-Phe-D-Leu
  8. Drug

    Pixofisiran

    go.drugbank.com/drugs/DB17294
    Experimental

    Synonyms: Rna, (a-g-a-a-g-u-u-g-g-c-a-u-g-g-u-a-g-c-c-c-u-u-g-g-g), complex with rna (c-c-c-a-a-g-g-g-c-u-a-c-c-a-u-g-c-c-a-a-c-u-u-c-u) (1:1)
  9. Drug

    Moxifloxacin

    go.drugbank.com/drugs/DB00218
    ApprovedInvestigational

    Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for ...

    Products: Moxifloxacin Altan 400 mg/250 ml Infusionslösung
  10. Drug

    Beclomethasone dipropionate

    go.drugbank.com/drugs/DB00394
    ApprovedInvestigational

    [A180010] Compared to earlier corticosteroids such as [dexamethasone] and [prednisolone], beclomethasone dipropionate is reported to be less irritating to the nasal mucosa with a longer duration of action

    Products: Alti-beclomethasone Dipropionate Inhaler 50mcg/md