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OT-730
go.drugbank.com/drugs/DB16112InvestigationalOT-730 is under investigation in clinical trial NCT00753168 (Phase 1-2 Evaluation of OT-730 Eye Drops in Reducing the Intraocular Pressure in Patients With Ocular Hypertension or Open-angle Glaucoma).
Aloe vera leaf
go.drugbank.com/drugs/DB13906ApprovedInvestigationalAloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands. … The use of aloe vera in constipation, inflammatory disorders, cancer, ulcer, and diabetes has also been investigated [A32476].
Synonyms: Lu hui yeMixtures: Re-action EVitamin E
go.drugbank.com/drugs/DB00163ApprovedInvestigationalNutraceuticalVet approvedIn 1922, vitamin E was demonstrated to be an essential nutrient[A32448]. … Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol being the most biologically active[A176104].
International brands: Aquasol E, Amino-Opti-EMixtures: TL-Select, TL-Care DHAFenobam
go.drugbank.com/drugs/DB12931InvestigationalFenobam is under investigation in clinical trial NCT00637221 (Open Label Study Investigating Safety and Efficacy of Fenobam anhydrous 50 mg - 150 mg on Prepulse Inhibition Tests and Continuous Performance
alpha-Tocopherol acetate
go.drugbank.com/drugs/DB14003ApprovedAlpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. … Nevertheless, vitamin E is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals.
Synonyms: Vitamin E acetate, Vitamin E (alpha tocopherol acetate)Mixtures: Unique Propoli Toothpas te, the naked object DeBlack PackToothpasteDavesomeran
go.drugbank.com/drugs/DB17091ApprovedInvestigational[L43882] A phase 2 and 3 open-label study in participants 18 years or older who had previously received a two-dose primary series and one booster dose of Moderna COVID-19 Vaccine demonstrated that the … Similar to the previous Moderna COVID-19 vaccine, Moderna Bivalent vaccine encodes the full-length pre-fusion stabilized spike (S) protein to elicit an immune response.
Hexobarbital
go.drugbank.com/drugs/DB01355ExperimentalA barbiturate that is effective as a hypnotic and sedative.
Foreskin fibroblast (neonatal)
go.drugbank.com/drugs/DB10770ApprovedDermagraft has been combined with [DB10772] to create a drug beneficial to patients with open burn wounds [L2427]. … The device is available for commercial distribution in Australia, Canada, Finland, France, Hong Kong, Ireland, The Netherlands, New Zealand, Singapore, and The United Kingdom [L2418].
EN001
go.drugbank.com/drugs/DB33920ExperimentalEN001 is under investigation in clinical trial NCT07808905 (Evaluate the Efficacy and Safety of EN001 in Patients With Sarcopenia (Phase 1: Open-label, Dose-escalation, Single-center ; Phase2: Randomized
Fidanacogene elaparvovec
go.drugbank.com/drugs/DB16783ApprovedInvestigational[L49469] This approval was based on positive results demonstrated in the open-label, single-arm Phase 3 BENEGENE-2 study, where the annualized bleeding rate (ABR) was observed to be 1.3 for the 12 months … from week 12 to month 15 compared to an ABR of 4.43 for the pre-treatment period.