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Displaying results 331 - 340 of 3732 in total
  1. Drug

    Thonzylamine

    go.drugbank.com/drugs/DB11235
    Approved

    Thonzylamine is an antihistamine and anticholinergic drug. It is available as combination products with DB04837 or DB00388 for temporary relief of symptoms of common cold, hay fever (allergic rhinitis) or other upper respiratory allergies.

    Mixtures: Nasopen PE, Poly Hist PD
  2. Drug

    Diosmin

    go.drugbank.com/drugs/DB08995
    ApprovedInvestigational

    Diosmin is widely available over-the-counter and demonstrates a favourable a favorable safety profile.[A232890,T840,L33040]

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2C9 Inhibitors
  3. Drug

    Cetalkonium

    go.drugbank.com/drugs/DB11583
    ApprovedWithdrawn

    [L2137] Cetalkonium is approved by the FDA for its use in over-the-counter products as a skin protectant.[L2737] By Health Canada, it is also approved for its use in over-the-counter products.[L1113]

  4. Drug

    Raxibacumab

    go.drugbank.com/drugs/DB08902
    ApprovedInvestigational

    Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons.

    Synonyms: PA mAb
  5. Drug

    Betula pendula tar oil

    go.drugbank.com/drugs/DB11361
    ApprovedNutraceutical

    [L2870] Betula pendula tar oil has been approved for its utilization in over-the-counter product combinations by Health Canada.

  6. Drug

    Erlotinib

    go.drugbank.com/drugs/DB00530
    ApprovedInvestigational

    Recent studies demonstrate that erlotinib is also a potent inhibitor of JAK2V617F, which is a mutant form of tyrosine kinase JAK2 found in most patients with polycythemia vera (PV) and a substantial proportion … This finding introduces the potential use of erlotinib in the treatment of JAK2V617F-positive PV and other myeloproliferative disorders.

    Categories: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors, P-glycoprotein inhibitors
  7. Drug

    Hydroxychloroquine

    go.drugbank.com/drugs/DB01611
    ApprovedInvestigational

    [L8072] A recent study reported a fatality in the group being treated with hydroxychloroquine for COVID-19.[A192546]

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  8. Indication

    Early Estrogen Receptor Positive Breast Cancer

    go.drugbank.com/conditions/DBCOND0173171
    Drugs: Goserelin
    Synonyms: Early Estrogen Receptor Positive Breast Cancer
  9. Indication

    Metastatic Estrogen Receptor Positive Breast Cancer

    go.drugbank.com/conditions/DBCOND0129603
    Drugs: Tamoxifen
    Synonyms: Metastatic Estrogen Receptor Positive Breast Cancer
  10. Drug

    Sildenafil

    go.drugbank.com/drugs/DB00203
    ApprovedInvestigational

    Although the medication has historically been most popularly recognized as Pfizer's brand name Viagra, sildenafil is currently available generically and even as a non-prescription over the counter medication

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Pb-sildenafil