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Somatostatin
go.drugbank.com/drugs/DB09099ApprovedInvestigationalWithdrawn[DB00104] is a long-acting analogue of somatostatin that inhibits the release of a number of hormones, and is clinically used to relieve symptoms of uncommon gastroenteropancreatic endocrine tumours, as … It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InhibitorsProducts: SOMATOSAN 3 MG IV INFUZYON ICIN 1 AMPUL, DELT-SOMAT®Pirenzepine
go.drugbank.com/drugs/DB00670ApprovedWithdrawnIt is generally well tolerated by patients. … It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence.
Synonyms: 11-((4-Methyl-1-piperazinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-oneCategories: Heterocyclic Compounds, 2-RingQuinagolide
go.drugbank.com/drugs/DB09097ApprovedWithdrawnIt is typically present in the hydrochloride salt form and is marketed as oral tablets under the brand name Norprolac contained as a racemate. … Quinagolide exists as a racemate and its relevant clinical activity is mediated predominantly by the (-) enantiomer.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (+-)-N,N-Diethyl-N'-((3R*,4aR*,10aS*)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo(g)quinolin-3-yl)sulfamideDienestrol
go.drugbank.com/drugs/DB00890ApprovedWithdrawnDienestrol is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. … Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy.
Synonyms: 4,4'-Hydroxy-γ,δ-diphenyl-β,δ-hexadiene, p,p'-(Diethylideneethylene)diphenolAsenapine
go.drugbank.com/drugs/DB06216ApprovedInvestigationalDeveloped by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with … It is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009.
Categories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor AntagonistsMegestrol acetate
go.drugbank.com/drugs/DB00351ApprovedInvestigationalVet approvedAs the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer. … 17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester.
Synonyms: 17α-Acetoxy-6-dehydro-6-methylprogesterone, 17alpha-Acetoxy-6-dehydro-6-methylprogesteroneCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesHelium
go.drugbank.com/drugs/DB09155ApprovedInvestigationalVet approvedHelium is a second most abundant chemical element in the universe with symbol He and atomic number 2. … It is a colorless, odorless, tasteless, non-toxic, inert, monatomic gas located at the top of the noble gases on the periodic table.
Mixtures: HELONTIX® 60, HELONTIX® 70Imiquimod
go.drugbank.com/drugs/DB00724ApprovedInvestigationalImiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. … Miquimod is also used to treat a skin condition of the face and scalp called actinic keratoses and certain types of skin cancer called superficial basal cell carcinoma.
Synonyms: 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine, 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinolineInternational brands: Li DiGuanabenz
go.drugbank.com/drugs/DB00629ApprovedWithdrawnGuanabenz is an alpha-2 selective adrenergic agonist used as an antihypertensive agent.
Synonyms: N-(2,6-DICHLOROBENZYLIDENE)-N'-AMIDINOHYDRAZINE, 2-((2,6-DICHLOROPHENYL)METHYLENE)HYDRAZINECARBOXIMIDAMIDECategories: Cytochrome P-450 Substrates, Adrenergic alpha-2 Receptor AgonistsWL-1002
go.drugbank.com/drugs/DB05346ExperimentalWL-1002 is developed by Winston Laboratories which is a topical cream formulation of 075% zucapaicin (also known as civamide), for the treatment of pain due to osteoarthritis.