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Oxaprotiline
go.drugbank.com/drugs/DB09307ExperimentalBoth enantiomers have antidepressant effects but levoprotiline also is an antihistamine and dextroprotiline has many other pharmacological actions.
DG041
go.drugbank.com/drugs/DB05027ExperimentalIt block the formation of blood clots mediated through inflammation in atherosclerotic plaques but without increasing bleeding risk.
Mipomersen
go.drugbank.com/drugs/DB05528ApprovedMipomersen sodium, which was known as the investigational drug, isis-301012, is the salt form of a synthetic phosphorothioate oligonucleotide. Mipomersen sodium prevents the formation of apo B-100, resulting in a decrease in the levels o...
CoronaVac
go.drugbank.com/drugs/DB15806InvestigationalIt was developed by propagating the SARS-CoV-2 CN2 strain inside Vero Cells and inactivating it with B-propiolactone[A219481;A219758]. … CoronaVac, previously known as PiCoVacc, is a SARS-CoV-2 purified, inactivated, and adsorbed vaccine candidate developed by SinoVac Biotech Corporation[A219758].
Davunetide
go.drugbank.com/drugs/DB12613InvestigationalDavunetide is the first drug to improve memory performance by impacting the mechanisms that lead to physical damage in the brain caused by neurofibrillary tangles, one of the two established pathological
Ceftiofur
go.drugbank.com/drugs/DB11485ExperimentalVet approvedIt is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product. … It is resistant to hydrolysis by beta-lactamase, and has activity against both Gram-positive and Gram-negative bacteria. E. coli strains resistant to ceftiofur have been reported.
Malathion
go.drugbank.com/drugs/DB00772ApprovedMalathion is a parasympathomimetic organophosphate compound that is used as an insecticide for the treatment of head lice. Malathion is an irreversible cholinesterase inhibitor and has low human toxicity.
Salsalate
go.drugbank.com/drugs/DB01399ApprovedInvestigationalSalsalate is a nonsteroidal anti-inflammatory agent for oral administration. Salsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of synthesis and release of prostaglandins. The usefulness o...
Pradefovir mesylate
go.drugbank.com/drugs/DB05478InvestigationalPradefovir is activated through oxidation that is mediated by cytochrome P-450 (CYP) 3A4, which is predominantly expressed in the liver.
Edodekin alfa
go.drugbank.com/drugs/DB15631Investigationalinvestigation in clinical trial NCT01468896 (Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That Is Recurrent, Metastatic, or Cannot Be Removed by