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Displaying results 3401 - 3410 of 10000 in total
  1. Drug

    MK-886

    go.drugbank.com/drugs/DB16739
    Experimental

    MK-886 is an experimental inhibitor of leukotriene synthesis.

  2. Drug

    MK-4965

    go.drugbank.com/drugs/DB08460
    Experimental

    MK-4965 is an HIV-1 reverse transcriptase inhibitor.

  3. Drug

    Sipuleucel-T

    go.drugbank.com/drugs/DB06688
    ApprovedInvestigational

    Sipuleucel-T is a personalized, autologous, cellular immunotherapy. Sipuleucel-T is a therapeutic cancer vaccine for prostate cancer.

  4. Pathway

    Cardiolipin Biosynthesis CL(10:0/10:0/10:0/10:0)

    smpdb.ca/view/SMP0175274
    Metabolic

    Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  5. Pathway

    Acylcarnitine (10Z,12E)-Pentadeca-10,12-dienoylcarnitine

    smpdb.ca/view/SMP0124236
    Metabolic

    (10Z,12E)-Pentadeca-10,12-dienoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (10Z,12E)-pentadeca-10,12-dienoyl-CoA reacts with L-carnitine to form (10Z,12E)-pentadeca-10,12-dienoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  6. Drug

    Edasalonexent

    go.drugbank.com/drugs/DB15010
    Investigational

    Edasalonexent is under investigation in clinical trial NCT01511900 (A Multiple Ascending Dose Study of CAT-1004 in Patients With Type 2 Diabetes).

  7. Drug

    SynKIR-110

    go.drugbank.com/drugs/DB17365
    Investigational

    SynKIR-110 are autologous T cells genetically engineered to express an anti-mesothelin killer immunoglobulin-like receptor-chimeric antigen receptor (KIR-CAR).

    Synonyms: SynKIR-110
  8. Drug

    Lepunafusp alfa

    go.drugbank.com/drugs/DB19011
    Investigational

    Lepunafusp alfa is under investigation in clinical trial NCT04453085 (An Extension Study of JR-171-101 Study in Patients With MPS I).

  9. Pathway

    De Novo Triacylglycerol Biosynthesis TG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))

    smpdb.ca/view/SMP0016175
    Metabolic

    A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
  10. Pathway

    Cardiolipin Biosynthesis CL(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))

    smpdb.ca/view/SMP0027489
    Metabolic

    Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate