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Flunisolide
go.drugbank.com/drugs/DB00180ApprovedFlunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions. … It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves activation of glucocorticoid receptors.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: Aerobid-M, FLUNISOLIDE EGPenton protein
go.drugbank.com/bio_entities/BE0001571TargetHAdV-2Major capsid protein that self-associates to form penton base pentamers, each in the shape of a pentagon, situated at the 12 vertices of the pseudo T=25 capsid.
Synonyms: Penton base proteinBronopol
go.drugbank.com/drugs/DB13960ApprovedFirst synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives … The agent is largely available commercially as an antibacterial for a variety of industrial purposes while it is predominantly available for purchase as a pet animal litter antibacterial at the domestic
5-Hydroxymethylfurfural
go.drugbank.com/drugs/DB12298InvestigationalAes-103 has been used in trials studying the treatment and prevention of Hypoxia, Anemia, Sickle Cell, and Sickle Cell Disease.
Synonyms: 5-(Hydroxymethyl)furfural, 5-(Hydroxymethyl)-2-furfuralDrotaverine
go.drugbank.com/drugs/DB06751ApprovedWithdrawnDrotaverine has been used in the symptomatic treatment of various spastic conditions, such as gastrointestinal diseases, biliary dyskinesia, and vasomotor diseases associated with smooth muscle spasms. … It is approved for use in Thailand as oral tablets or intramuscular injections.[L22689]
Products: SPACOVIN (40 )Temafloxacin
go.drugbank.com/drugs/DB01405ApprovedWithdrawnIt was first approved for use in the U.S. market in 1992, but was withdrawn shortly due to the reports of serious adverse reactions, such as allergic reactions and hemolyric anemia, resulting in three
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsSI-109
go.drugbank.com/drugs/DB32603ExperimentalSI-109 is a potent, small-molecule inhibitor of the STAT3 SH2 domain.[A275443]
CoronaVac
go.drugbank.com/drugs/DB15806InvestigationalThe antibodies were found to neutralize 10 representative SARS-CoV-2 strains. As of August 2020, the vaccine is being tested in numerous human clinical trials assessing its safety and immunogenicity. … It was developed by propagating the SARS-CoV-2 CN2 strain inside Vero Cells and inactivating it with B-propiolactone[A219481;A219758].