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Oxolamine
go.drugbank.com/drugs/DB13216ApprovedOxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant . It is listed as a prescription drug in New Zealand legislation . Oxolamine is also approved in Taiwan for the treatment of respir...
Mixtures: ASE-COLD 120 mg+50mg+1mg/5 ml PEDİATRİK ŞURUPCategories: Cough and Cold PreparationsNisoldipine
go.drugbank.com/drugs/DB00401ApprovedBy inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. … It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation.
Categories: Calcium-Regulating Hormones and AgentsTechnetium Tc-99m tetrofosmin
go.drugbank.com/drugs/DB09160Approved[A31592] Technetium Tc-99m tetrofosmin was developed by GE Healthcare and FDA approved on February 9, 1996. … The radioisotope, technetium-99m, is chelated by two 1,2-bis[di-(2-ethoxyethyl)phosphino]ethane ligands which belong to the group of diphosphines and which are referred to as tetrofosmin.
Categories: Indicators and ReagentsInterferon alfa-n3
go.drugbank.com/drugs/DB00018ApprovedPurified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and ProteinsAsfotase alfa
go.drugbank.com/drugs/DB09105ApprovedInvestigationalAsfotase alfa was first approved by Pharmaceuticals and Medicals Devices Agency of Japan (PMDA) on July 3, 2015, then approved by the European Medicine Agency (EMA) on August 28, 2015, and was approved … By replacing deficient ALP, treatment with Asfotase Alfa aims to improve the elevated enzyme substrate levels and improve the body's ability to mineralize bone, thereby preventing serious skeletal and
Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismPhenformin
go.drugbank.com/drugs/DB00914ApprovedWithdrawn(From Martindale, The Extra Pharmacopoeia, 30th ed, p290) … A biguanide hypoglycemic agent with actions and uses similar to those of metformin.
Categories: Alimentary Tract and Metabolism, phenformin and sulfonylureasDarolutamide
go.drugbank.com/drugs/DB12941ApprovedInvestigational[A189054,A189063] Darolutamide was developed by Bayer HealthCare Pharmaceuticals Inc. and approved by the FDA on July 30th, 2019.[L10887] … The goal of treatment with darolutamide is to delay the progression of prostate cancer to metastatic disease, increasing quality of life and life expectancy for those with advanced prostate cancer.
Categories: Antineoplastic and Immunomodulating Agents, Hormone Antagonists and Related AgentsSibeprenlimab
go.drugbank.com/drugs/DB18919ApprovedInvestigational[L54633] APRIL is a member of the tumour necrosis factor superfamily that regulates and modulates activated B cells. … [A274853, A274858] Sibeprenlimab is a humanized immunoglobulin G2 (IgG2) monoclonal antibody produced by Chinese Hamster Ovary (CHO) cells.
Categories: Amino Acids, Peptides, and ProteinsAcetic acid
go.drugbank.com/drugs/DB03166ApprovedInvestigational(Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or fungus. … Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent.
Mixtures: Hydrocortisone and Acetic Acid, Hydrocortisone and Acetic AcidCategories: Indicators and Reagents, Genito Urinary System and Sex HormonesTofersen
go.drugbank.com/drugs/DB14782ApprovedInvestigational[A259028,A259033] Tofersen was granted accelerated approval from the FDA on April 25, 2023, as the first treatment for adults with ALS caused by SOD1 mutation. … [L46133] Continual FDA approval is contingent on clinical benefits from ongoing trials, particularly the Phase 3 ATLAST study in people with presymptomatic SOD1-ALS.
Categories: Nucleic Acids, Nucleotides, and Nucleosides