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Displaying results 3421 - 3430 of 8700 in total
  1. Drug

    Oxyphenisatin

    go.drugbank.com/drugs/DB04823
    ApprovedWithdrawn

    It may cause jaundice.

    Synonyms: 3,3-Bis(p-hydroxyphenyl)oxindole, 3,3-Bis(p-hydroxyphenyl)-2-indolinoneCategories: Drugs for Constipation
  2. Target

    Vitamin D-binding protein

    go.drugbank.com/bio_entities/BE0001141
    CarrierTargetHumans

    Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation

    Synonyms: DBP-maf, Gc-MAF
  3. Drug

    Avanafil

    go.drugbank.com/drugs/DB06237
    Approved

    In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both [sildenafil] and [vardenafil] but less selectivity than [tadalafil], suggesting a relatively

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  4. Drug

    Cinnamaldehyde

    go.drugbank.com/drugs/DB14184
    Approved

    Sensitivity to cinnamaldehyde may be identified with a clinical patch test.

  5. Drug

    Brecanavir

    go.drugbank.com/drugs/DB04887
    Investigational

    Brecanavir (VX-385) an orally active aspartic protease inhibitor (PI), under investigation by Vertex and GlaxoSmithKline for the treatment of HIV. … In December of 2006 GSK announced a decision to discontinue the development of brecanavir for the treatment of HIV. The decision was based on issues regarding the formulation of the drug.

  6. Drug

    Ancrod

    go.drugbank.com/drugs/DB05099
    ApprovedWithdrawn

    The defribrinogenation of blood results in an anticoagulant effect. … and oxygen to portions of the brain, for which phase III trials are currently being conducted.

  7. Drug

    Pemirolast

    go.drugbank.com/drugs/DB00885
    ApprovedWithdrawn

    As an ophthalmic aqueous sterile solution, pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitis. … It is a mast cell stabilizer that acts as an antiallergic agent.

  8. Drug

    Testosterone cypionate

    go.drugbank.com/drugs/DB13943
    ApprovedInvestigational

    Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  9. Drug

    PF-232798

    go.drugbank.com/drugs/DB14813
    Investigational

    PF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects).

    Categories: CCR5 Receptor AntagonistsSynonyms: PF-00232798
  10. Drug

    Cobicistat

    go.drugbank.com/drugs/DB09065
    ApprovedInvestigational

    Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human immunodeficiency virus (HIV). … Increasing systemic exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and a decreased side effect profile.

    Categories: Antiinfectives for Systemic Use, Antivirals used in combination for the treatment of HIV infections