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Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins
go.drugbank.com/drugs/DB15729InvestigationalAutologous stem cells are those derived from a patient’s own cells while allogeneic stem cells are derived from that of a donor. … Lipoaspiration, also known as liposuction, is a possible method for extraction. This is followed by purification and expansion of the cells in vitro.
Bamlanivimab
go.drugbank.com/drugs/DB15718ApprovedInvestigationalBamlanivimab (LY-CoV555, also known as LY3819253), is a synthetic monoclonal antibody (mAb) derived from one of the first blood samples in the United States from a patient who recovered from COVID-19. … [A224039, L15311, L15316] Bamlanivimab is a neutralizing IgG1κ mAb directed against the SARS-CoV-2 spike (S) protein, which is described to block viral entry into human cells.
L523S
go.drugbank.com/drugs/DB06498Investigational[A175909] It has been investigated as a lung cancer vaccine. … According to Nemunaitis J., et al, "L523S is an immunogenic lung cancer antigen that has demonstrated preclinical safety when the gene is injected intramuscularly as an expressive plasmid (pVAX/L523S)
Lapretolimod
go.drugbank.com/drugs/DB20120InvestigationalLapretolimod has a monoisotopic molecular weight of 1745.28 Da. … Lapretolimod is a small molecule drug. The usage of the INN stem '-tolimod' in the name indicates that Lapretolimod is a toll-like receptor (TLR) agonist.
Synonyms: Glucopyranosyl lipid aUpacicalcet
go.drugbank.com/drugs/DB20023InvestigationalUpacicalcet has a monoisotopic molecular weight of 351.03 Da. … Upacicalcet is a small molecule drug. The usage of the INN stem '-calcet/-calcet-' in the name indicates that Upacicalcet is a calcium-sensing receptor (CaSR) agonist.
Atuveciclib
go.drugbank.com/drugs/DB20084InvestigationalAtuveciclib has a monoisotopic molecular weight of 387.12 Da. … Atuveciclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Atuveciclib is a cyclin dependant kinase inhibitor.
Bavtavirine
go.drugbank.com/drugs/DB21527InvestigationalBavtavirine has a monoisotopic molecular weight of 416.17 Da. … Bavtavirine is a small molecule drug. The usage of the INN stem '-virine' in the name indicates that Bavtavirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
Cenacitinib
go.drugbank.com/drugs/DB21735InvestigationalCenacitinib has a monoisotopic molecular weight of 431.15 Da. … Cenacitinib is a small molecule drug. The usage of the INN stem '-citinib' in the name indicates that Cenacitinib is a Janus kinase inhibitor.
Oditrasertib
go.drugbank.com/drugs/DB21526InvestigationalOditrasertib has a monoisotopic molecular weight of 295.11 Da. … Oditrasertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Oditrasertib is a serine/threonine kinase inhibitor.
Ruserontinib
go.drugbank.com/drugs/DB21555InvestigationalRuserontinib has a monoisotopic molecular weight of 443.25 Da. … Ruserontinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Ruserontinib is a tyrosine kinase inhibitor.