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Displaying results 3431 - 3440 of 8575 in total
  1. Drug

    Salsalate

    go.drugbank.com/drugs/DB01399
    ApprovedInvestigational

    The usefulness of salicylic acid, the active in vivo product of salsalate, in the treatment of arthritic disorders has been established. … Salsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of synthesis and release of prostaglandins.

    Products: Disalcid Tab 500mg, Disalcid - Tab 500mg
  2. Drug

    Janssen COVID-19 Vaccine

    go.drugbank.com/drugs/DB15857
    ApprovedInvestigational

    As of June 2020, a Phase 1/2 clinical trial in adult humans was announced to evaluate the safety, immunogenicity, and efficacy of the ad26.COV.S vaccine in 1045 healthy adults between the ages of 18-55 … The vaccine was created in collaboration with Johnson and Johnson (J&J), Janssen Pharmaceutical, and the Beth Israel Deaconess Medical Center.

  3. Drug

    Clotiazepam

    go.drugbank.com/drugs/DB01559
    ApprovedIllicit

    Clotiazepam is a thienodiazepine, not approved for sale in the U.S. or Canada, but has been approved in the U.K. It is a schedule IV drug in Canada.

  4. Drug

    Nafarelin

    go.drugbank.com/drugs/DB00666
    ApprovedInvestigational

    Nafarelin has been used in the treatments of central precocious puberty and endometriosis.

    Products: Synarel Nas Sol 2mg/ml
  5. Drug

    Talorasib

    go.drugbank.com/drugs/DB21686
    Experimental

    The usage of the INN stem '-rasib' in the name indicates that Talorasib is a Ras protein inhibitor. Talorasib has a monoisotopic molecular weight of 604.24 Da.

  6. Drug

    Uric acid

    go.drugbank.com/drugs/DB08844
    Investigational

    As a therapeutic agent, it is known that uric acid is increased in response to oxidative stress, and as such, uric acid acts as an antioxidant. … In one country, Spain, uric acid is an investigational drug in a phase 3 trial studying its effects as an adjunct to alteplase in acute ischemic stroke.

  7. Drug

    Collagen-polyvinylpyrrolidone

    go.drugbank.com/drugs/DB16525
    Investigational

    Collagen-polyvinylpyrrolidone is a copolymer generated from a mixture of type I collagen and low-molecular-weight PVP that has undergone γ irradiation[A227733].

  8. Drug

    Ulimorelin

    go.drugbank.com/drugs/DB12128
    Investigational

    Ulimorelin is a novel small molecule ghrelin agonist being developed by Tranzyme Pharma as a first-in-class treatment for both POI and diabetic gastroparesis, serious medical conditions in which motility

  9. Drug

    Apronalide

    go.drugbank.com/drugs/DB13221
    Approved

    Apronalide has been withdrawn from the market in many other countries due to patient development of thrombocytopenic purpura [A174814].

  10. Drug

    Osugacestat

    go.drugbank.com/drugs/DB12006
    Investigational

    Osugacestat (BMS-906024) has been used in trials studying the treatment of Cancer, Lymphoblastic Leukemia, Acute T-cell, and Precursor T-Cell Lymphoblastic Lymphoma.

    Synonyms: (2R,3S)-N1-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-2,3-bis(3,3,3-trifluoropropyl)succinamide, Butanediamide, N1-((3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-2,3-bis(3,3,3-trifluorophenyl)-, (2R,3S)-