Clotiazepam

DB01559ApprovedIllicitSmall molecule

Clotiazepam is a thienodiazepine used to manage anxiety disorders and insomnia. Clotiazepam is a thienodiazepine, not approved for sale in the U.S. or Canada, but has been approved in the U.K.

Mechanism: Clotiazepam acts at the benzodiazepine receptors (BZD). This agonizes the action of GABA, increasing the frequency of opening of the channel chlorinates and penetration of the ions chlorinates through the ionophore. Increase in membrane polarization decreases the probability of discharge of neurons.
Curator reviewed
Primary indication: For the treatment of anxiety disorders.Curator reviewed · 2 structured indications
Formula / weight: C₁₆H₁₅ClN₂OS · 318.821 g/mol (avg)
Code names: Y 6047

Resolves to

Compound

UNIIZCN055599VCAS33671-46-4ChEMBLCHEMBL1697737ChEBI31425PubChem2811KEGGD01328

Clinical / RWD

RxNorm2622ATCN05BA21PharmGKBPA164752437

Structure

InChIKeyCHBRHODLKOZEPZ-UHFFFAOYSA-NSMILESCCC1=CC2=C(S1)N(C)C(=O)CN=C2C1=CC=CC=C1Cl

Targets

P30536TSPO

What you can answer from here — as of September 23, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

878Drug interactionsStructured to mechanism, not free text

1Clinical trialPhase, status and sponsor resolved per trial

2Structured indicationsCondition, population, route and combination as fields, not prose

7ContraindicationsEach with its own population and attribute set

6Marketed productsAcross 1 country and 2 labellers

1ATC codeIncluding every combination product, plus 11 drug categories

10+ReferencesStructured and connected to the statements they support

Which drugs share a target with Clotiazepam, and which of those have an active Phase 3 trial?

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