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Anumigilimab
go.drugbank.com/drugs/DB16359InvestigationalCSL324 is a fully human anti-G-CSFR antibody shown to have the ability to control G-CSF-mediated neutrophilia in cynomolgus macaques.
VLTS-589
go.drugbank.com/drugs/DB05430InvestigationalVLTS-589 consists of plasmid encoding the angiomatrix protein Del-1 in conjunction with poloxamer 188 for the treatment of peripheral vascular disease.
Meclocycline
go.drugbank.com/drugs/DB13092InvestigationalMeclocycline is under investigation in clinical trial NCT00385515 (Efficacy of SNX-1012 in the Treatment of Oral Mucositis) .
Mixtures: MECLODERM F, MECLODERM FNabiximols
go.drugbank.com/drugs/DB14011InvestigationalIn contrast to THC's weak agonist activity, CBD has been shown to act as a negative allosteric modulator of the cannabinoid CB1 receptor, the most abundant G-Protein Coupled Receptor (GPCR) in the body … Nabiximols (tradename Sativex®) is a whole plant extract from the Cannabis species _Cannabis sativa L._ that has been purified into the active components CBD (cannabidiol) and THC (delta-9-tetrahydrocannabinol
Categories: Cannabinoid Receptor Agonists, Cytochrome P-450 SubstratesAmenamevir
go.drugbank.com/drugs/DB11701InvestigationalAmenamevir has been used in trials studying the treatment of Herpes Zoster, Herpes Simplex, Herpes Genitalis, and Safety of Amenamevir.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersGSK-364735
go.drugbank.com/drugs/DB13119InvestigationalGSK-364735 (Naphthyridinone) has been used in trials studying the treatment of HIV-1 Infection and Infection, Human Immunodeficiency Virus.
Categories: Heterocyclic Compounds, 2-RingLenomorelin
go.drugbank.com/drugs/DB11895InvestigationalLenomorelin has been investigated for the treatment and basic science of Cancer, Alcoholism, Metabolism, Hypopituitarism, and Frailty Syndrome, among others.
AZD-1236
go.drugbank.com/drugs/DB11961InvestigationalAZD1236 has been used in trials studying the basic science and treatment of Cystic Fibrosis and Chronic Obstructive Pulmonary Disease.
Categories: Heterocyclic Compounds, 1-RingBMS-986094
go.drugbank.com/drugs/DB11966InvestigationalINX-08189 has been used in trials studying the treatment of Hepatitis C, HCV (Genotype 1), and Hepatitis C Virus.
Categories: Heterocyclic Compounds, 2-RingRilotumumab
go.drugbank.com/drugs/DB11972InvestigationalRilotumumab has been investigated for the treatment of Cancer, Lung Cancer, Solid Tumors, Gastric Cancer, and Prostate Cancer, among others.