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Cinchocaine
go.drugbank.com/drugs/DB00527ApprovedVet approvedIt is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
Mixtures: ULTRAPROCT %0,09+%0,09+%0,5 MERHEM, 10 G, ULTRAPROCT SUPOZITUAR, 10 ADETGlasdegib
go.drugbank.com/drugs/DB11978ApprovedInvestigational[A40310] The great lipophilicity of this group of compounds brought interest to further modification. … [A258498,A258503] Although the efficacy of glasdegib monotherapy is limited, the landmark Phase 2 Bright AML 1003 trial showed a superior overall survival and complete response when glasdegib is combined
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEfbemalenograstim alfa
go.drugbank.com/drugs/DB18704ApprovedInvestigationalEfbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration … This approval was contingent on positive results observed in two pivotal Phase 3 Studies GC-627-04 and GC-627-05 in the US and Europe respectively.[L48887]
Synonyms: Rh g-csf fc fusion protein f-627, Recombinant dimeric g-csf fusion protein f627Keratin, type I cytoskeletal 16
go.drugbank.com/bio_entities/BE0009086TargetHumansRegulates epidermal innate immunity and inflammatory signaling in response to barrier disruption. Required for normal palmoplantar epidermal differentiation and nail unit structure (By similarity) … Forms heteropolymers with type II keratins KRT6A and KRT6B, assembling into keratin intermediate filament networks that contribute to cytoskeletal resilience of palm, sole, nail bed and oral mucosa (PubMed
Polypeptides: Keratin, type I cytoskeletal 16Synonyms: CK-16, Keratin-16Serine/threonine-protein kinase 16
go.drugbank.com/bio_entities/BE0009542TargetHumansAble to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins
Polypeptides: Serine/threonine-protein kinase 16XPro1595
go.drugbank.com/drugs/DB16454InvestigationalXPro1595 is an investigational dominant-negative protein that neutralizes soluble TNF.
Synonyms: HOMOSAPIENS TUMOR NECROSIS FACTOR,SOLUBLE FORM (V1>M, R31>C, C69>V, Y87>H, C101>A, A145>R), MONOMER, PEGYLATED ON CYSTEINE 31 : S-((3RS)-(2-((3-(.OMEGA., SOLUBLE TUMOR NECROSIS FACTOR (1-METHIONINE,31-CYSTEINE,69-VALINE,87-HISTIDINE,101-ALANINE,145-ARGININE) (HUMAN CONSTRUCT XPRO1595), 31-THIOETHER WITH .ALPHA.-(3-((3-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYLIstradefylline
go.drugbank.com/drugs/DB11757ApprovedInvestigationalIstradefylline, or KW6002, was developed by Kyowa Hakko Kirin in Japan for the treatment of Parkinson's disease as an adjunct to standard therapy. … [A184067] Istradefylline is indicated as an adjunct treatment to [levodopa] and [carbidopa] for Parkinson's disease.[L8237] This drug was first approved in Japan on 25 March 2013.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesMestranol
go.drugbank.com/drugs/DB01357ApprovedWithdrawnIt must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL contraceptives.
Mixtures: Norinyl 1/50 28 Tab, Norinyl 1/50 21 TabCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesRacepinephrine
go.drugbank.com/drugs/DB11124ApprovedRacepinephrine is a racemic mixture consisting of d-DB00668 and l-DB00668 enantiomers. Epinephrine is a non-selective α- and β-adrenergic receptor agonist. It is a bronchodilator used in the temporary relief of mild symptoms of intermitt...
Mixtures: Racord Two No 10, Sil Trax Plus No 10Products: Sil Trax Epi No 8, Sil Trax Epi No 9Periungual Warts
go.drugbank.com/conditions/DBCOND0077510Drugs: CantharidinSynonyms: Periungual wart, Periungual wart (disorder)