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PAC-113
go.drugbank.com/drugs/DB05756InvestigationalPAC-113 an anti-fungal, for the treatment of oral candidiasis infections. It is a 12 amino-acid antimicrobial peptide derived from a naturally occurring histatin protein found in saliva. … PAC-113 is targeting oral Candida infections in immunocompromised patients and patients with salivary dysfunction.
Hypochlorous acid
go.drugbank.com/drugs/DB14135InvestigationalAn oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.
Categories: Compounds used in a research, industrial, or household settingProducts: AN XIN Disinfectant, INCARE All in one PlusImidurea
go.drugbank.com/drugs/DB14075ApprovedImidurea is an antimicrobial preservative used in cosmetics. It acts as a formaldehyde releaser.
Methyl undecenoyl leucinate
go.drugbank.com/drugs/DB11272ApprovedMethyl undecenoyl leucinate is an active ingredient in whitening creams. … It is an α-MSH antagonist that inhibits melanin synthesis and tyrosinase activity and reduces expression of various melanogenic genes.
Kinetin
go.drugbank.com/drugs/DB11336ApprovedWhile kinetin is used in tissue cultures to produce new plants, it is also found in cosmetic products as an anti-aging agents. … It was shown to naturally exist in DNA of organisms including humans and various plants.
Arachidonic Acid
go.drugbank.com/drugs/DB04557ApprovedInvestigationalWithdrawnAn unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. … It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. [PubChem]
Colfosceril palmitate
go.drugbank.com/drugs/DB09114ApprovedWithdrawnColfosceril palmitate is a synthetic pulmonary surfactant administered in infants with respiratory distress syndrome. … [T70] It was developed by Burroughs Wellcome and it was FDA approved on August 6, 1990.[L1109] Nowadays colfosceril palmitate is under the state of canceled post-marketing.
Avapritinib
go.drugbank.com/drugs/DB15233ApprovedInvestigationalAvapritinib was granted FDA approval on 9 January 2020 [L40363] and EMA approval on 24 September 2020.[L41464]
MPI-674
go.drugbank.com/drugs/DB05749ExperimentalMPI-674 is an aromatase inhibitor (AI) with a well-established, multi-year chronic safety and tolerability profile. … AIs are a class of drugs that reduce the amount of estrogen circulating in the body by binding to and inhibiting the enzyme aromatase, which is responsible for converting certain hormones to estrogen.
Luseogliflozin
go.drugbank.com/drugs/DB12214InvestigationalLuseogliflozin has been used in trials studying the treatment of Diabetes Melltius, Type 2.
Categories: Drugs Used in Diabetes