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Gramicidin D
go.drugbank.com/drugs/DB00027ApprovedInvestigationalGramcidin D is a heterogeneous mixture of three antibiotic compounds, gramicidins A, B and C, making up 80%, 6%, and 14% respectively all of which are obtained from the soil bacterial species Bacillus brevis and called collectively grami...
Ardeparin
go.drugbank.com/drugs/DB00407ApprovedWithdrawnArdeparin, marketed under the US trade name Normiflo, is a low molecular weight heparin (LMWH) anticoagulant used for the prevention of postoperative venous thrombosis. Ardeparin is derived via peroxide degradation of heparin extracted f...
4-Hydroxytestosterone
go.drugbank.com/drugs/DB01485IllicitInvestigationalIt is specifically the 17-hydroxylated analog to formestane. … It is an anabolic steroid with no therapeutic indications, which is prohibited from use in sports by the World Anti-Doping Agency.
Zimelidine
go.drugbank.com/drugs/DB04832ApprovedWithdrawnZimelidine has been banned worldwide due to serious, sometimes fatal, cases of central and/or peripheral neuropathy known as Guillain-Barré syndrome and due to a peculiar hypersensitivity reaction involving many organs including skin exa...
Procyclidine
go.drugbank.com/drugs/DB00387ApprovedInvestigationalA muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.
Products: Procyclid Tab 5mg, Kemadrin Tab 5mgRiluzole
go.drugbank.com/drugs/DB00740ApprovedInvestigationalA glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi.
Products: RILUZOL - CT 50 MG, RILUTEK 50 MGMPI-674
go.drugbank.com/drugs/DB05749ExperimentalIt is developed for the treatment of several serious women’s health conditions including endometrial thinning prior to endometrial ablations in premenopausal women with abnormal uterine bleeding (AUB).
Metrizamide
go.drugbank.com/drugs/DB01578ExperimentalIt is also used as a resorbable, non-ionic contrast medium.
Citrulline
go.drugbank.com/drugs/DB00155InvestigationalNutraceuticalIt is made from ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle. It is also produced from arginine as a by-product of the reaction catalyzed by NOS family. … Its name is derived from citrullus, the Latin word for watermelon, from which it was first isolated.
Taberminogene vadenovec
go.drugbank.com/drugs/DB05011ExperimentalEG004 has completed a Phase II trial, this being the first part of the Phase II/III study for which it has received approval from the US Recombinant DNA Advisory Committee (RAC).