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Displaying results 3481 - 3490 of 10000 in total
  1. Drug

    VAD-044

    go.drugbank.com/drugs/DB17697
    Investigational

    VAD-044 is an allosteric AKT inhibitor developed by Vaderis Therapeutics AG. It is being investigated for the treatment of Hereditary Hemorrhagic Telangiectasia.[L46098]

    Synonyms: 6-(4-((1S,3S)-1-amino-3-hydroxycyclobutyl)phenyl)-1-ethyl-7-phenyl-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one
  2. Drug

    Hycanthone

    go.drugbank.com/drugs/DB14061
    Experimental

    Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used.

    Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 3-RingSynonyms: 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one, 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one
  3. Drug

    N,N-[2,5-O-di-2-fluoro-benzyl-glucaryl]-di-[1-amino-indan-2-ol]

    go.drugbank.com/drugs/DB02629
    Experimental

    Synonyms: N,N-[2,5-O-di-2-fluoro-benzyl-glucaryl]-di-[1-amino-indan-2-ol]
  4. Drug

    MEM 1003

    go.drugbank.com/drugs/DB05547
    Investigational

    MEM 10003 was under investigation in clinical trial NCT00257673 (Safety and Efficacy of MEM 1003 Versus Placebo in Patients With Mild to Moderate Alzheimer's Disease) for the treatment of Alzheimer's Disease

    Synonyms: CALCIUM CHANNEL, L TYPE, ALPHA-1 POLYPEPTIDE, ISOFORM 1, CARDIAC MUSCLE, VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1C
  5. Drug

    Nadofaragene firadenovec

    go.drugbank.com/drugs/DB17381
    ApprovedInvestigational

    Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). … [A255106,L44381] Nadofaragene firadenovec also has a manageable adverse event profile. Compared to [pembrolizumab], a smaller proportion of patients experienced grade 3-4 adverse events (4% vs 12.7%).

    Synonyms: Replication-deficient adenovirus type 5 (ad5) vector encoding the human interferon alpha 2 (ifna2, interferon alpha-2b) gene under the control of the cytomegalovirus (cmv) immediate-early enhancer/promoter
  6. Drug

    Radgocitabine

    go.drugbank.com/drugs/DB11667
    Investigational

    2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine has been used in trials studying the treatment of Advanced Colorectal Cancer.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine
  7. Drug

    Sulfamethazine

    go.drugbank.com/drugs/DB01582
    ApprovedVet approvedWithdrawn

    A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.

    Mixtures: Tylan 40 Sulfa-G Premix, KHC TRIMETHOMIX 400/80MG/G PREMIX POWDERSynonyms: N(1)-(4,6-Dimethyl-2-pyrimidyl)sulfanilamide, N(1)-(4,6-Dimethyl-2-pyrimidinyl)sulfanilamide
  8. Drug

    LDN-193189

    go.drugbank.com/drugs/DB18051
    Experimental

    Synonyms: 4-(6-(4-(piperazin-1-yl)phenyl_pyrazolo[1,5-a]pyrimidin-3-yl)quinoline, Quinoline, 4-(6-(4-(1-piperazinyl)phenyl)pyrazolo(1,5-a)pyrimidin-3-yl)-Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Nutlin-3

    go.drugbank.com/drugs/DB17039
    Experimental

    Nutlin-3 is a small molecule inhibitor that targets p53-Mdm2 interaction.[A253057]

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-piperazinone, 4-(((4r,5s)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-(4-methoxy-2-(1-methylethoxy)phenyl)-1h-imidazol-1-yl)carbonyl)-, rel-, Nutlin-3
  10. Drug

    Flurbiprofen

    go.drugbank.com/drugs/DB00712
    ApprovedInvestigational

    Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity.

    Mixtures: MAJEZIK DUO %5 + %0.25 TOPIKAL JEL, 50 G, MERDEX DUO %5 + %0.25 TOPIKAL JEL, 50 GCategories: Cytochrome P-450 Substrates, Non COX-2 selective NSAIDS