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Displaying results 341 - 350 of 10000 in total
  1. Drug

    Anti-CD19 CAR-T cells

    go.drugbank.com/drugs/DB21913
    Investigational

    CD19 CAR-T is under investigation in clinical trial NCT05618041 (The Safety and Efficay Investigation of CAR-T Cell Therapy for Patients with Hematological Malignancies).

    Synonyms: CD19 Chimeric Antigen Receptor (CAR) T cells, CD19 CAR T
  2. Drug

    Zavegepant

    go.drugbank.com/drugs/DB15688
    ApprovedInvestigational

    Zavegepant (BHV-3500) is a calcitonin gene-related peptide (CGRP) receptor antagonist. … Zavegepant is a third-generation CGRP receptor antagonist that is small in size and highly soluble. Due to its pharmacological properties, it can be administered intranasally.

    Synonyms: 1-piperidinecarboxamide, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-n-((1r)-1-((7-methyl-1h-indazol-5-yl)methyl)-2-(4-(1-methyl-4-piperidinyl)-1-piperazinyl)-2-oxoethyl)-Categories: Calcitonin Gene-Related Peptide Receptor Antagonists, Calcitonin Gene-Related Peptide (CGRP) Antagonists
  3. Drug

    Suratadenoturev

    go.drugbank.com/drugs/DB18672
    Investigational

    Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.

    Synonyms: A recombinant replication-competent adenovirus type 5 (Ad-5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and replaced by an expression cassette containing, A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human telomerase reverse transcriptase (hTERT) and IRES, respectively.
  4. Drug

    Sodium fluoride

    go.drugbank.com/drugs/DB09325
    ApprovedInvestigational

    Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as [Fluoride ion F-18]. … Now, sodium fluoride may be found in a variety of gels, varnishes, rinses, toothpaste products, and fluoride treatments provided in dental care.

    Mixtures: VITAMINS A, C, D and FLUORIDE, E-Z CupsCategories: Compounds used in a research, industrial, or household setting
  5. Drug

    Phellinus linteus mycelium

    go.drugbank.com/drugs/DB14282
    Investigational

    Phellinus linteus mycelium is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Song Gen Mycelium
  6. Drug

    Famtozinameran

    go.drugbank.com/drugs/DB17088
    ApprovedInvestigational

    [L43917] Famtozinameran is an mRNA vaccine encoding the S glycoprotein of SARS-CoV-2 Omicron variant lineages BA.4 and BA.5. … BA.4, BA.5) which, although similar, may behave differently from one another.

    Mixtures: Comirnaty Original & Omicron Ba.4/ba.5, Comirnaty Original & Omicron Ba.4/ba.5
  7. Indication

    Hormone Receptor Positive Breast Carcinoma

    go.drugbank.com/conditions/DBCOND0119681
    Drugs: Olaparib
    Synonyms: Hormone-receptor-positive Breast Cancer, Hormone Receptor-Positive Breast Carcinoma
  8. Drug

    Galcanezumab

    go.drugbank.com/drugs/DB14042
    ApprovedInvestigational

    Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin gene-related peptide (CGRP). … A pregnancy exposure registry has been established to evaluate the safety of this drug in pregnant women.[L42060]

    Categories: Calcitonin Gene-Related Peptide Receptor Antagonists, Calcitonin Gene-Related Peptide (CGRP) AntagonistsProducts: EMGALİTY 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET, EMGALİTY 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 ADET
  9. Drug

    Atogepant

    go.drugbank.com/drugs/DB16098
    ApprovedInvestigational

    Atogepant is an oral antagonist of calcitonin gene-related peptide (CGRP) receptors indicated for the prevention of episodic migraine headaches. … [A239094] The "gepants" family of drugs, including atogepant, are comparatively well-tolerated[A189207,L38739] and may provide a desirable treatment option for patients struggling with adverse reactions

    Categories: Calcitonin Gene-Related Peptide Receptor Antagonists, Calcitonin Gene-Related Peptide (CGRP) AntagonistsProducts: AQUIPTA® 60 MG, AQUIPTA® 10 MG
  10. Drug

    Erenumab

    go.drugbank.com/drugs/DB14039
    ApprovedInvestigational

    Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines … CGRP receptor, which is believed to play a critical role in migraine [L2823].

    Categories: Calcitonin Gene-Related Peptide Receptor Antagonists, Calcitonin Gene-Related Peptide (CGRP) AntagonistsProducts: PASURTA® 70MG/ML, PASURTA® 140 MG /ML