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Donepezil
go.drugbank.com/drugs/DB00843ApprovedInvestigationalIn 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. … [L7916,L7937] A donepezil transdermal delivery system, Adlarity, was approved by the FDA in March 2022 for the treatment of Alzheimer's dementia.
Mixtures: DOMINGO 5/5/80 MG EFERVESAN TABLET, 30 ADET, DOMINGO 5/5/80 MG EFERVESAN TABLET, 90 ADETCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingValproic acid
go.drugbank.com/drugs/DB00313ApprovedInvestigationalValproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. … It is currently a compound of interest in the field of oncology for its anti-proliferative effects and is the subject of many clinical trials in a variety of cancer types.
Categories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexSynonyms: 2-n-propyl-n-valeric acid, n-DPAAtazanavir
go.drugbank.com/drugs/DB01072ApprovedInvestigationalAtazanavir is distinguished from other PIs in that it can be given once daily (rather than requiring multiple doses per day) and has lesser effects on the patient's lipid profile (the amounts of cholesterol … Atazanavir (formerly known as BMS-232632) is an antiretroviral drug of the protease inhibitor (PI) class.
Mixtures: ANCEF ® R, ANCEF ® RCategories: P-glycoprotein inducers, P-glycoprotein inhibitorsAscorbic acid
go.drugbank.com/drugs/DB00126ApprovedInvestigationalNutraceuticalA six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. … Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
Mixtures: Re Kar C Plus, Rhume Et De LA Grippe (extra-fort)Categories: ascorbic acid (vit C), Vitamin C and analoguesBeroctocog alfa
go.drugbank.com/drugs/DB14473ApprovedInvestigationalMixtures: OPTIVATE(R), HAEMATE PProducts: FACTOR VIII DE COAGULACION HUMANO 500 UI, DRIED FACTOR VIII FRACTION 500 UI + FACTOR DE VON WILLEBRAND 800 UIMebeverine
go.drugbank.com/drugs/DB12554ApprovedInvestigationalWithdrawnMebeverine has been investigated for the treatment of Irritable Bowel Syndrome and Post-cholecystectomy Gastrointestinal Spasms.
Products: DUSPATALIN® CÁPSULA DE LIBERACIÓN PROLONGADA 200 MG, DUSPATALIN CÁPSULA DE LIBERACIÓN PROLONGADA 200 MG.Tofacitinib
go.drugbank.com/drugs/DB08895ApprovedInvestigationalTofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: XELJANZ® XR 11 MG TABLETAS DE LIBERACIÓN MODIFICADA, XELJANZ®5MGBimatoprost
go.drugbank.com/drugs/DB00905ApprovedInvestigationalBimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. … [L6910] It was initially approved by the FDA in 2001 for ocular hypertension and later approved for hypothrichosis in 2008, as eyelash growth became a desirable adverse effect for patients using this drug
Mixtures: BEMATORİN-T 0,3 MG + 5 MG/1 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET, GANFORT®Categories: Cytochrome P-450 Substrates, Prostaglandins F, SyntheticOndansetron
go.drugbank.com/drugs/DB00904ApprovedInvestigationalWithdrawnA competitive serotonin type 3 receptor antagonist. … [L5221] The FDA withdrew its approval for the use of all intravenous drug products containing more than 16 mg of ondansetron hydrochloride in a single dose, due to a high risk of QT prolongation.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Ran-ondansetron, Van-ondansetronCL-315555
go.drugbank.com/drugs/DB18757ExperimentalCL-315555 is the C isomer of [Verteporfin].
Synonyms: Bpd-ma(sub c), Verteporfin-mac