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Displaying results 341 - 350 of 10000 in total
  1. Drug

    Finasteride

    go.drugbank.com/drugs/DB01216
    ApprovedInvestigational

    Compared to alpha-blockers that focus on providing the rapid relief of symptoms, 5α-reductase inhibitors aim to target the underlying disease by blocking the effects of the primary androgen involved in … [L6244,L10565] In 1998, it was approved by the FDA to treat male pattern hair loss.

    Categories: Drugs Used in Benign Prostatic Hypertrophy, Skin and Mucous Membrane AgentsSynonyms: (5alpha,17beta)-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide
  2. Drug

    Xylometazoline

    go.drugbank.com/drugs/DB06694
    Approved

    In some countries, it is available as combination products with [ipratropium], [domiphen], or [dexpanthenol]. … [A228508] Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies.

    Products: NASENSPRAY SINE AL 1MG/ML, NASENSPRAY SINE AL0.5MG/ML
  3. Drug

    Chlorpheniramine

    go.drugbank.com/drugs/DB01114
    ApprovedInvestigational

    A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications.

    Mixtures: COUGH - EN, Sinu-C SuspensionSynonyms: 1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine, 3-(p-chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine
  4. Drug

    Levosimendan

    go.drugbank.com/drugs/DB00922
    ApprovedInvestigationalWithdrawn

    Levosimendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure). … Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels.

    Categories: Compounds used in a research, industrial, or household settingProducts: Levosimendan Carinopharm 12,5 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, LEVOSIMENDAN EG
  5. Drug

    Sodium bicarbonate

    go.drugbank.com/drugs/DB01390
    ApprovedInvestigational

    Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

    Mixtures: Tetrofosmin ROTOP 0,23 mg Kit für ein radioaktives Arzneimittel, ENOProducts: BICARBONATO DE SODIO EN POLVO - 45, Skin protectant
  6. Drug

    Carboplatin

    go.drugbank.com/drugs/DB00958
    ApprovedInvestigational

    Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.[L32253] Early clinical studies of carboplatin were performed in 1982. … [A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.[L32248]

    Categories: Compounds used in a research, industrial, or household settingProducts: CARBOPLATINO SUN, PLATINWAS 150 MG 10MG/ML ENJ. FLAKON, 1 ADET
  7. Drug

    Terlipressin

    go.drugbank.com/drugs/DB02638
    ApprovedInvestigational

    [A2601, A2602, A2603, A2604, A2605] It was also studied in hepatorenal syndrome (HRS) and variceal bleeding.[A252672] The drug was first approved by the FDA in September 2022.[L43217] … [L43217] As a potent vasopressor, terlipressin has been investigated in various shock states and conditions with diminished vasomotor tone.

    Products: TERLIPRESSINA SUN
  8. Drug

    Tazobactam

    go.drugbank.com/drugs/DB01606
    ApprovedInvestigational

    and mortality in hospitalized patients. … Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved by the FDA in 2014[FDA label], providing wider antibacterial coverage for gram-negative infections

    Mixtures: Zosyn in Galaxy Containers, Zosyn in Galaxy ContainersProducts: TAZOCIN EF
  9. Drug

    Phendimetrazine

    go.drugbank.com/drugs/DB01579
    ApprovedIllicit

    Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances and in the US since 1970.

    Products: Fendique ER, Phendimetrazine Tartrate ER
  10. Drug

    Copper(II) dithiosemicarbazone

    go.drugbank.com/drugs/DB16963
    Investigational

    Synonyms: Diacetyl(n(4)-methylthiosemicarbazonato) copper (ii), Copper, ((2,2'-(1,2-dimethyl-1,2-ethanediylidene)bis(n-methylhydrazinecarbothioamidato-.kappa.n2,.kappa.s))(2-))-, (sp-4-2)-