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Displaying results 341 - 350 of 2348 in total
  1. Drug

    Manganese gluconate

    go.drugbank.com/drugs/DB11141
    Approved

    Manganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O. It is typically obtained by reacting manganese carbonate with gluconic acid in aqueous medium and then crystallizing the product to fo...

  2. Drug

    Benzatropine

    go.drugbank.com/drugs/DB00245
    ApprovedInvestigational

    Benztropine, with the chemical formula 3alpha-diphenylmethoxytropane, is a tropane-based dopamine inhibitor used for the symptomatic treatment of Parkinson's disease. It is a combination molecule between a tropane ring, similar to cocain...

    Categories: Membrane Transport Modulators
  3. Drug

    Lorpiprazole

    go.drugbank.com/drugs/DB09195
    Approved

    Lorpiprazole is a serotonin antagonist and reuptake inhibitor used for the treatment of major depressive disorder. It is a piperazinyl-triazole derivative.

  4. Drug

    Tenapanor

    go.drugbank.com/drugs/DB11761
    ApprovedInvestigational

    [A185492] As an inhibitor of the sodium/hydrogen exchanger isoform 3 (NHE3) transporter, it is the first and currently only medication within its class[A185489,A185492,A185495] and therefore exists as

  5. Drug

    Volixibat

    go.drugbank.com/drugs/DB13914
    Investigational

    Volixibat is a selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT), a transmembrane protein primarily expressed by enterocytes of the ileum. … Also known as the ileal bile acid transporter (IBAT), ASBT is primarily responsible for the enterohepatic recirculation of bile acids and ultimately for hepatic lipid and glucose metabolism [A32120].

  6. Drug

    ETC-588

    go.drugbank.com/drugs/DB05456
    Experimental

    LUV are capable of transporting excess cholesterol from the vasculature to the liver for eventual elimination as part of the reverse lipid transport (RLT) pathway.

  7. Drug

    Estriol

    go.drugbank.com/drugs/DB04573
    ApprovedInvestigationalVet approved

    A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During pregnancy, large amount of estriol is produced by the placenta. Isomers w...

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemProducts: ESTRIOL 2MG FEM JENAPHARM, Natural Revita Vaginal Moisturizer
  8. Drug

    Tilapertin

    go.drugbank.com/drugs/DB20461
    Experimental

    The usage of the INN stem '-pertin' in the name indicates that Tilapertin is a glycine transporter inhibitor. Tilapertin has a monoisotopic molecular weight of 378.16 Da.

  9. Drug

    Simvastatin

    go.drugbank.com/drugs/DB00641
    ApprovedInvestigational

    protein 1B1)-mediated transport. … which catalyzes the conversion of HMG-CoA to mevalonic acid and is the third step in a sequence of metabolic reactions involved in the production of several compounds involved in lipid metabolism and transport

    Mixtures: ZETEZE-SM TABLETS 10+80MG, ZETEZE-SM TABLETS 10+40 MG
  10. Drug

    Estrone

    go.drugbank.com/drugs/DB00655
    Approved

    Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol. It is produced primarily in the ovaries,...

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System